ID F1Z1D5_9STRE Unreviewed; 322 AA.
AC F1Z1D5;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit {ECO:0000313|EMBL:EGE54565.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:EGE54565.1};
GN Name=acoA {ECO:0000313|EMBL:EGE54565.1};
GN ORFNames=SPB_0815 {ECO:0000313|EMBL:EGE54565.1};
OS Streptococcus parauberis NCFD 2020.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=873447 {ECO:0000313|EMBL:EGE54565.1, ECO:0000313|Proteomes:UP000003732};
RN [1] {ECO:0000313|EMBL:EGE54565.1, ECO:0000313|Proteomes:UP000003732}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCFD 2020 {ECO:0000313|EMBL:EGE54565.1,
RC ECO:0000313|Proteomes:UP000003732};
RA Stanhope M.J., Durkin A.S., Hostetler J., Kim M., Radune D., Singh I.,
RA Town C.D.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGE54565.1}.
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DR EMBL; AEUT02000001; EGE54565.1; -; Genomic_DNA.
DR RefSeq; WP_003105156.1; NZ_AEUT02000001.1.
DR AlphaFoldDB; F1Z1D5; -.
DR GeneID; 66816605; -.
DR eggNOG; COG1071; Bacteria.
DR HOGENOM; CLU_029393_5_0_9; -.
DR Proteomes; UP000003732; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGE54565.1}.
FT DOMAIN 15..311
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 322 AA; 35589 MW; 28D52D2CAA9CD436 CRC64;
MVTVSKEKHL DMFLKMERIR EFDSRINKLV RRGFVQGMTH FSVGEEAANV GAVAHLTYDD
IIFSNHRGHG QSIAKDMDLN KMMAELAGKA TGVSKGRGGS MHLADIEKGN YGTNGIVGGG
YALAVGAALT QQYKGTNNIA VAFSGDGATN EGSFHESVNM AATWKLPVIF FIINNRYGIS
MNINNATNTP HLYTRAEAYG IPGFYCEDGN DVLAVYETME KAVEHVRGGN GPAIVEVESY
RWFGHSTADA GKYRTKEEVA SWKEKDPMIK YRTYLTKEGI VTDEELDAIQ EQVKKEIDDA
YEFAQNSPDP ELSVAFEDVW VD
//
