ID   F2CA16_STRSA            Unreviewed;       284 AA.
AC   F2CA16;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=Helix-turn-helix domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF9386_2022 {ECO:0000313|EMBL:EGF13246.1};
OS   Streptococcus sanguinis SK330.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=888813 {ECO:0000313|EMBL:EGF13246.1, ECO:0000313|Proteomes:UP000005955};
RN   [1] {ECO:0000313|EMBL:EGF13246.1, ECO:0000313|Proteomes:UP000005955}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK330 {ECO:0000313|EMBL:EGF13246.1,
RC   ECO:0000313|Proteomes:UP000005955};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGF13246.1}.
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DR   EMBL; AFBD01000008; EGF13246.1; -; Genomic_DNA.
DR   AlphaFoldDB; F2CA16; -.
DR   PATRIC; fig|888813.3.peg.1991; -.
DR   HOGENOM; CLU_047530_0_2_9; -.
DR   Proteomes; UP000005955; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR048211; RodZ-like.
DR   NCBIfam; NF041534; rodZ_Strepcoccus; 1.
DR   PANTHER; PTHR34475; -; 1.
DR   PANTHER; PTHR34475:SF1; CYTOSKELETON PROTEIN RODZ; 1.
DR   Pfam; PF13413; HTH_25; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        114..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   284 AA;  31041 MW;  D6F901D3D7EB4E38 CRC64;
     MKNRNKGKVR MRKKTIGEVL KLARTNQGLS LEELSNKTDI QQDLLEALER NDYDLLPSPF
     YARSFLRKYA WAVDLDESII LEAYEAGEMI VFDEVALAAD EEFRSRKNKN KTSFLPLFYF
     LLLASAIAAF VAYYIWSYAH TNSVSFKASN SNYSLVSSTS TNNQKTSFSS ADSKSVSSSA
     SKLTVSGSGE NLIAEYSEAS QPVKVTVSVE QTTNLVSISD SELAEGVTLS PEKSSQTVSL
     EPGNKYLITL APVKGVTVTI EGQKLDTSAL TSDSGTISLN ITKG
//