ID   F2CGN0_STRSA            Unreviewed;       360 AA.
AC   F2CGN0;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Arsenical resistance operon transcription repressor (ArsR) {ECO:0000313|EMBL:EGF17905.1};
GN   ORFNames=HMPREF9391_2025 {ECO:0000313|EMBL:EGF17905.1};
OS   Streptococcus sanguinis SK408.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=888818 {ECO:0000313|EMBL:EGF17905.1, ECO:0000313|Proteomes:UP000004826};
RN   [1] {ECO:0000313|EMBL:EGF17905.1, ECO:0000313|Proteomes:UP000004826}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK408 {ECO:0000313|EMBL:EGF17905.1,
RC   ECO:0000313|Proteomes:UP000004826};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGF17905.1}.
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DR   EMBL; AFBE01000011; EGF17905.1; -; Genomic_DNA.
DR   RefSeq; WP_002917771.1; NZ_GL878560.1.
DR   AlphaFoldDB; F2CGN0; -.
DR   PATRIC; fig|888818.3.peg.1975; -.
DR   HOGENOM; CLU_068463_0_0_9; -.
DR   Proteomes; UP000004826; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13412; HTH_24; 1.
DR   SMART; SM00418; HTH_ARSR; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50987; HTH_ARSR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT   DOMAIN          269..360
FT                   /note="HTH arsR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50987"
SQ   SEQUENCE   360 AA;  41569 MW;  77E0B7456CB7CAAF CRC64;
     MKNRNCILFL VRSGVCVRRE ESVGVKLVHY RSKLYEFLMV PAIVSRDDKH MCKDLRQNQK
     ELLLDVQPHY DKLYQALLPL KSELVAVSLF EGATVGLAPL FYLYLLEKGE DPANPHDLLE
     CLKKLDAEQI IYCLSLKLSA GEVAERHPEE LLAFIENSDK SPENKWYWYQ AIQHPEKLRD
     QLVSLLERVF ELYQPIYEQF EQEVLAFEQE FSLSDVMDDE EQNAKLLEKD TQVFVLSPMF
     IDSFLEKVPD FTSYSLVLST RSSQLSKAES GLDDETLALS LKTLSDETRY KVLIELIQPH
     AKNKDIAKKL GLTRASISFH TQKLLNSGLL ELVVDDDSVK YTVNKELIQK IIEKFKQDLT
//