ID F2IXC1_POLGS Unreviewed; 499 AA.
AC F2IXC1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Phospholipase D {ECO:0000256|ARBA:ARBA00018392};
DE AltName: Full=Choline phosphatase {ECO:0000256|ARBA:ARBA00029594};
GN Name=cls {ECO:0000313|EMBL:ADZ70439.1};
GN OrderedLocusNames=SL003B_2013 {ECO:0000313|EMBL:ADZ70439.1};
OS Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Polymorphum.
OX NCBI_TaxID=991905 {ECO:0000313|EMBL:ADZ70439.1, ECO:0000313|Proteomes:UP000008130};
RN [1] {ECO:0000313|EMBL:ADZ70439.1, ECO:0000313|Proteomes:UP000008130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 25793 / CGMCC 1.9160 / SL003B-26A1
RC {ECO:0000313|Proteomes:UP000008130};
RX PubMed=21478361; DOI=10.1128/JB.00333-11;
RA Li S.G., Tang Y.Q., Nie Y., Cai M., Wu X.L.;
RT "Complete genome sequence of Polymorphum gilvum SL003B-26A1T, a crude oil-
RT degrading bacterium from oil-polluted saline soil.";
RL J. Bacteriol. 193:2894-2895(2011).
CC -!- FUNCTION: Could be a virulence factor. {ECO:0000256|ARBA:ARBA00003145}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; CP002568; ADZ70439.1; -; Genomic_DNA.
DR RefSeq; WP_013652757.1; NC_015259.1.
DR AlphaFoldDB; F2IXC1; -.
DR STRING; 991905.SL003B_2013; -.
DR KEGG; pgv:SL003B_2013; -.
DR PATRIC; fig|991905.3.peg.2063; -.
DR eggNOG; COG1502; Bacteria.
DR HOGENOM; CLU_038053_1_0_5; -.
DR OrthoDB; 9762009at2; -.
DR Proteomes; UP000008130; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR CDD; cd09155; PLDc_PaCLS_like_1; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR027379; CLS_N.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR Pfam; PF13396; PLDc_N; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000008130};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 237..264
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 412..439
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 499 AA; 55379 MW; 6ED9E28A36683C9F CRC64;
MEGASSQQGG PDLAQELIHD ASVADLFLNN LGIIAAVTAA LYALAAVCAV REIMNSRSAQ
GSVAWLLSLF FLPFPTALLY LVFGWKQFDD YAAVQRKMGR FERAARAEDL GLGHAEATTD
WPVLAKVANL PFLAGNACEL LIDGEATFDS ILDGIAAARQ TILVQFFIVR DDAIGRRLAD
LLIERARAGV RVYFLYDEIG CKSLAKSYLR RLKDNGIRVS GFNETHRYLR MTGPMRINYR
NHRKVVVVDN THAWVGGHNV GDEYLGRDPD FGHWRDTHVK VSGPAALGCT LSFAEDWHWA
NGTVLDIGPA GPVEQLGDEP VLVMPTGPAD PMEDCAIAFS EAISRARRRL WIVSPYFVPG
PEIQTGLYAA ALRGVDVRVL LPEKADHRLV WLASHAHADD LVSQGIKVYR YQKGFLHQKV
VLVDDQLTSI GTANFDNRSF RINFEITLWF THPRMIEKVA AMLETDFADA RQTGPDDLEQ
RAYLFRLLAQ SAKLFSPVL
//
