ID F2LIK5_BURGS Unreviewed; 293 AA.
AC F2LIK5;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=2-hydroxy-3-oxopropionate reductase {ECO:0000313|EMBL:AEA62799.1};
GN OrderedLocusNames=bgla_2g03230 {ECO:0000313|EMBL:AEA62799.1};
OS Burkholderia gladioli (strain BSR3).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=999541 {ECO:0000313|EMBL:AEA62799.1, ECO:0000313|Proteomes:UP000008316};
RN [1] {ECO:0000313|EMBL:AEA62799.1, ECO:0000313|Proteomes:UP000008316}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BSR3 {ECO:0000313|EMBL:AEA62799.1,
RC ECO:0000313|Proteomes:UP000008316};
RX PubMed=21478339; DOI=10.1128/JB.00420-11;
RA Seo Y.S., Lim J., Choi B.S., Kim H., Goo E., Lee B., Lim J.S., Choi I.Y.,
RA Moon J.S., Kim J., Hwang I.;
RT "Complete genome sequence of Burkholderia gladioli BSR3.";
RL J. Bacteriol. 193:3149-3149(2011).
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DR EMBL; CP002600; AEA62799.1; -; Genomic_DNA.
DR RefSeq; WP_013689131.1; NC_015376.1.
DR AlphaFoldDB; F2LIK5; -.
DR STRING; 999541.bgla_2g03230; -.
DR GeneID; 66462026; -.
DR KEGG; bgd:bgla_2g03230; -.
DR eggNOG; COG2084; Bacteria.
DR HOGENOM; CLU_035117_0_2_4; -.
DR Proteomes; UP000008316; Chromosome 2.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 2..158
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 166..283
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 170
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 293 AA; 31384 MW; 1AA3485EBE0EA90E CRC64;
MKVGFIGIGV MGQPMALNLA RAGIELVIWN RSPERCAPLR EAGAQVADTL DEVYRQARIV
ILMMATDEAL DAVLGRGTPA FAARVADHLI VHMGTVSAEY SRGLDADIRA AGGRYVEAPV
SGSRKPAEAG QLVAMLAGEP ADVEEVRPLL KPMCHESVVC GPVPTGLLMK LSVNTFLIPM
VTAVAEASHL ARRYGLDMQQ FQKVLDAGPM ASAVSRVKID KLVREDFEVQ ASIADVLKNN
RLAAEAARNA NLASPLLDTC FELYTETLKL GHGGEDMAAV VRAIEARTDK RQG
//
