ID   F2Q3F2_TRIEC            Unreviewed;      1049 AA.
AC   F2Q3F2;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=TEQG_08810 {ECO:0000313|EMBL:EGE08670.1};
OS   Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse ringworm
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=559882 {ECO:0000313|Proteomes:UP000009169};
RN   [1] {ECO:0000313|Proteomes:UP000009169}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4606 / CBS 127.97 {ECO:0000313|Proteomes:UP000009169};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
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DR   EMBL; DS995784; EGE08670.1; -; Genomic_DNA.
DR   AlphaFoldDB; F2Q3F2; -.
DR   VEuPathDB; FungiDB:TEQG_08810; -.
DR   eggNOG; KOG2063; Eukaryota.
DR   HOGENOM; CLU_004190_1_1_1; -.
DR   Proteomes; UP000009169; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF10366; Vps39_1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
FT   DOMAIN          18..349
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          52..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          458..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        460..488
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        517..536
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1049 AA;  115981 MW;  0CE3199DA33B4DFA CRC64;
     MLTAFTARPL VEFRPRDKSK IESILTYGDR LLVGLNTGSL RIYRVNEVNV DEAETRAGDD
     TEAQDGSGDG GGAVQPSPAT KPTDLLRELE KFSWYKIEQL AIIKEANILL SLSNGHVSIH
     DLQSYELHEQ LTRTKGATTF AVTSNIEKDQ DTGVPSIVSR LAVAVKRKLM LWTWQDMELE
     DDATEITLVS GIKTVTWANG TKLLAGLSSS YVLVDVVTRE VTDIVGPGSI GGAGGSDTGR
     LGGVGASMSY IGMGGATPKP LATRLCEGQM LLAKDVNSHF IDTDGNGLKR RQIPWTVAPE
     AVGYSYPYLL ALQDASKGIL EVRNPETLSL LQSVSLPSAT MIHIPQPNIS LAHAGKGFLV
     ASGRVIWRMS ALDYDSQIDG LVEQGNLDEA ISLLGMLEDA LLNDKEGRLR EIKLRKAQTL
     FEKQKYRKSL DLFTEVSAPP EIVIRLFPKL IAGELSSIEE ETAPESSESS EENPSQPENG
     TSIHSAEPTT PDDKPKVKNG AYAPSVTSFL RGRPDDASET GSMRGKPADL KEPDKRLEGK
     DLKAAVYELQ GFLADIRRRL SRFISPDGTL KEPSVNVDKS DETTQSMLKT LGISSDDLEN
     IDMSQKLRET ATLVDTTLFR ALMFATPTLA GSLFRIDNFC DPEVVMEKLE QTARYGDLID
     FLFGKRLHRS ALEQLKKFGQ KEAGEEISPE LQGPKRTVAY LQNLPPDMID LILEFAEWPL
     RSDPELGMEI FLTDTENAET LPRQKVLEFL NGIDAKLAIK YSEHVINELN DLTPDIHFRL
     LTLYLERILK SKKSKDVFPA EDEREECKNR FLKMLETSEQ YSPAKMLDRL PRDDPEFFEP
     RAVTLSKMGQ HRQALEIYVF KLDNPAKAEE YCNRVHLSDS TSTKQRAVPY GSSPAVEDEE
     ARPSIYHTLL SLYLSPPHGY ESRYGPAIEI LARHGSRLPA SSTLSLIPGS LPIHDLEFYF
     RSRIRAANSI LNQGRIISSL HKIQSAETEA ALRLGDNVGS NKGRNRCITV SEDRVCSHCH
     KRLGGSVISV FPNNTVVHLG CANRLGSAT
//