ID F2QC81_STROU Unreviewed; 2148 AA.
AC F2QC81;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Zinc metalloproteinase, putative {ECO:0000313|EMBL:CBZ00249.1};
GN OrderedLocusNames=SOR_0587 {ECO:0000313|EMBL:CBZ00249.1};
OS Streptococcus oralis (strain Uo5).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=927666 {ECO:0000313|EMBL:CBZ00249.1, ECO:0000313|Proteomes:UP000008131};
RN [1] {ECO:0000313|EMBL:CBZ00249.1, ECO:0000313|Proteomes:UP000008131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Uo5 {ECO:0000313|EMBL:CBZ00249.1,
RC ECO:0000313|Proteomes:UP000008131};
RX PubMed=21460080; DOI=10.1128/JB.00321-11;
RA Reichmann P., Nuhn M., Denapaite D., Bruckner R., Henrich B., Maurer P.,
RA Rieger M., Klages S., Reinhard R., Hakenbeck R.;
RT "Genome of Streptococcus oralis strain Uo5.";
RL J. Bacteriol. 193:2888-2889(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR720602; CBZ00249.1; -; Genomic_DNA.
DR KEGG; sor:SOR_0587; -.
DR eggNOG; COG1196; Bacteria.
DR eggNOG; COG3583; Bacteria.
DR HOGENOM; CLU_000802_1_0_9; -.
DR Proteomes; UP000008131; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.160.20.110; -; 1.
DR Gene3D; 1.20.120.1850; Ebh helix bundles repeating unit (S and A modules); 2.
DR Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 4.
DR InterPro; IPR011098; G5_dom.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR InterPro; IPR011505; Peptidase_M26_C_dom.
DR InterPro; IPR008006; Peptidase_M26_N_dom.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF07554; FIVAR; 2.
DR Pfam; PF07501; G5; 4.
DR Pfam; PF07580; Peptidase_M26_C; 1.
DR Pfam; PF05342; Peptidase_M26_N; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM01208; G5; 4.
DR SUPFAM; SSF46997; Bacterial immunoglobulin/albumin-binding domains; 1.
DR PROSITE; PS51109; G5; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 249..329
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 355..435
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 450..530
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 545..625
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT REGION 205..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2148 AA; 238735 MW; 0FCF3F6B68FB7F85 CRC64;
MMKERLGMKR NYLGEKHQRF SLRKVSVGLV SALVGVFYLF SGGGSLSNVA ASEPTPSVTK
QIHYKYVTES ELSDQEKQLV VKELPQFAEE TDDTYYLIYR PTRQLPATGH SQLISSIAAG
AGIVLLVVAI KLGRDDRKKL ASFMLLTSLG SQLIAPTSLA LTNQMLADYN QELTVQVGET
LQSPLTIEGY QYVGYLKSQK EVKPSVDGKK ELNHSAPIDT PVQTSNGSQA QEEYRAQKPS
DAPVFEQPEL KVESKDTSRT EIIPFQVVEV EAADLPQGQT EVIQAGKNGS RTIVTRSYIL
NGQVIHTEEV SNQVTTEPTS EIRKVGSKVL SPTKPSPEES VSEKPTDAPV NEVPSLNVEE
KDVTTTVAEP YTRERVESDS LPVGQIKITQ AGQDGVRTIV TRQYMVDGKV ERSQELSNEV
TTPAVSEIVT VGTGPVSEKP TDAPVNEVPS LEVEEKDVTT TVAEPYTRER VESDSLPVGQ
TKITQAGQDG VRTIVTRQYM VDGKVERSQE ISNEVTTPAV SEIVTFGTAP VSEKPTDAPV
NEVPSLNVEE KDVTTTVAEP YPTKEVESAD LPLGQREVSQ AGQDGVRTIV IRQYLVDGKV
ENTEEISNTI TKEAVPQIIK VGTKPISTNA DHAPVEPEKG TLDLEPLHQL VEEADSIQKT
HQYFNDTTAD QESYKQAVAN AQALFETSHA SQEQVDSLKK ALETAKKNLD GQPVDKKTLG
VEFDMKDVTQ STVAYQYADE QAKLRYRRAL DQAKLVLDNP FANQALVDQV RTDLEAARQA
LDGVKRKPTL SLVRVEKEED KRQVSLSYHL TDATASYQSA KAQLYKGETL IKEVDLVDLA
QKLTLDDLDY YTPYTLKTVM KYDLGQGEQT SIEDQRPVQL DYKKVEIKDI DRIELYGKDG
SHYRRYLSLS EVPSDLNNYY VRIQSDKFKD MLLPVSKVTD KGNAYSVTVS ANQLVEGEGD
HYRPDYSFDF PKTPLSQEGI YTSFKALIEA MKSNPTGNFK LGADVSADEI QLEHSATSYV
PEEFSGSLTS RVDGKDYTIY NLAKPLFATL KNATIQQLTL KSAAVTGKDS IGTLASNAQN
ATITDVSVSG SLSGNKHIGG LVGVSQNTKL TNVAFKGSIT STQDGGQEYN IGGLVGNFHG
NQSLAQKSQA DVSIQVTGRN GDQRVGGLIG RLQNGARLET SYVTGSIQNG GHSGQVGGAI
GSTWNNGQVR NVLTSVKVQN GHAMTGDPYP EASVRDSYVL EGTTANRKDE RFVRSISEAD
AQAKRQSFGI TSNLTDQESL QQAYQHQTDY SRVRGAQESR KQAYENVEKL LPFYNKDFIV
HTANQLAEDD KLNKVALLDV VPMKDETLIT DVNSHKGEIN RLMLHYADKT IAYLDLTYKG
DFANGQIAEY SIADKNLLYT PEVFLSDYQS IKASVLEELK AVTYDSAAVR KVLGIGETAS
LDDLYLEKAF EQTKAELGQE LLKVLSVDKS INTLGPAVAD AISQKILQNK EAFMLGLTYL
NRWYNVNYGT FNTKDLNAYK FDFFGNQAAS TLDTIIALGN SGMGNLRAQN NFNAYRQSLA
KEKGKGDLFA YLESLRELFL PHKTNSEWFK ENTKAYIVEA RSSLPEIQAK QDNADRKSKY
TIKVYDRLTQ GDWGFKQMVL QLLTLPERDV FIISNMSTIA FGSFGSYRKE GGRVLSGEEL
HRHVEKLVDQ SAEWQRNHYD MWYNILSPNR KDTLFRRVIV TDGFFVYNDK GHQYWAPRND
KTSVAMYNFF GPAGKYHGDN GLGAFANGYE VFYVYDQMLG ASGTMVYTHE MTHNSDGSIY
FEGHGRREGE GPESFATGML ESVTNVSEKG LVLNSFYQGD KDSTSRYHTY DPVARFSSAD
ALRDYMHGVF DVLNLLDYVE GDIVTGVLTD QQKMKWYRKA ENYKFENTSY GKQAHADDRI
VPITAEEASK LKSVDALVDH NIIGRRDGWD TASFGRNGYY IVNMFASFYA ALDNPTGAPG
GLMFRRRAYE LLGDKGYQQG FVPYVSGQYS GQALKEGHKT YSIWNRGDVG VIGDDLILKN
LYGSQYESWK DLKKAMLNER YNKAQNFLRP ITIEFEAGKL DSKRQITISS YEELQDYMYL
AVLADASAKN IDRALSDSSK SSVAQLKYRI FNAYLRATDD FRQSIFER
//
