ID F2QCP8_STROU Unreviewed; 367 AA.
AC F2QCP8;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:CBZ00416.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:CBZ00416.1};
GN OrderedLocusNames=SOR_0754 {ECO:0000313|EMBL:CBZ00416.1};
OS Streptococcus oralis (strain Uo5).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=927666 {ECO:0000313|EMBL:CBZ00416.1, ECO:0000313|Proteomes:UP000008131};
RN [1] {ECO:0000313|EMBL:CBZ00416.1, ECO:0000313|Proteomes:UP000008131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Uo5 {ECO:0000313|EMBL:CBZ00416.1,
RC ECO:0000313|Proteomes:UP000008131};
RX PubMed=21460080; DOI=10.1128/JB.00321-11;
RA Reichmann P., Nuhn M., Denapaite D., Bruckner R., Henrich B., Maurer P.,
RA Rieger M., Klages S., Reinhard R., Hakenbeck R.;
RT "Genome of Streptococcus oralis strain Uo5.";
RL J. Bacteriol. 193:2888-2889(2011).
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
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DR EMBL; FR720602; CBZ00416.1; -; Genomic_DNA.
DR RefSeq; WP_001140467.1; NC_015291.1.
DR AlphaFoldDB; F2QCP8; -.
DR KEGG; sor:SOR_0754; -.
DR eggNOG; COG0287; Bacteria.
DR HOGENOM; CLU_055968_2_1_9; -.
DR Proteomes; UP000008131; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CBZ00416.1}.
FT DOMAIN 3..293
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 367 AA; 40902 MW; 1100D78C8636C4E4 CRC64;
MAKTIYIAGL GLIGASMALG IKRDHPDYEI LGYNRSQASR DIALERGMID RATDDFASFA
PLADVIILTL PIKQTIAFIK ELADLDLKEG VIISDAGSTK SAIVDAAEEH LAGNPVRFVG
AHPMAGSHKT GAASADVNLF ENAYYIFTPS SLTSPDTLEE MKDLLSGLHA RFIEIDAKEH
DRVTSQISHF PHILASSLME QTAVYAQEHE MARRFAAGGF RDMTRIAESE PGMWTSILLS
NRETILDRIA DFKERLDEVG QAISKGDEEQ IWNFFNQARA QRQAMEIHKR GGVDSSYDLY
VDVPDEEDVI LRILELLRGT SLVNIHINEE NREDVHGILQ ISFKNSQDLE RAERLITENT
DYTVVIK
//
