ID F2SII2_TRIRC Unreviewed; 1333 AA.
AC F2SII2;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=TERG_02670 {ECO:0000313|EMBL:EGD86413.2};
OS Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559305 {ECO:0000313|EMBL:EGD86413.2, ECO:0000313|Proteomes:UP000008864};
RN [1] {ECO:0000313|Proteomes:UP000008864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; GG700649; EGD86413.2; -; Genomic_DNA.
DR STRING; 559305.F2SII2; -.
DR VEuPathDB; FungiDB:TERG_02670; -.
DR eggNOG; KOG0128; Eukaryota.
DR HOGENOM; CLU_003925_0_0_1; -.
DR InParanoid; F2SII2; -.
DR OMA; LWARYIL; -.
DR OrthoDB; 3035286at2759; -.
DR Proteomes; UP000008864; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd12296; RRM1_Prp24; 1.
DR CDD; cd12297; RRM2_Prp24; 1.
DR CDD; cd12299; RRM4_Prp24; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034397; Prp24_RRM1.
DR InterPro; IPR034398; Prp24_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR031766; RRM_occluded.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR48025; OS02G0815200 PROTEIN; 1.
DR PANTHER; PTHR48025:SF22; OS02G0815200 PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 3.
DR Pfam; PF16842; RRM_occluded; 1.
DR SMART; SM00386; HAT; 2.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008864};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 852..924
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 925..1002
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1016..1092
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1142..1215
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 750..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..849
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1090..1139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1226..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 812..828
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1090..1127
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1236..1272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1293..1307
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1308..1333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1333 AA; 149283 MW; 29FC4CCAE696BB32 CRC64;
MDIRDLITPN SSRQEKAVRS PAPVPSPRPR SHRGNTPQTA WAGSGGVHGN GTGPRQTQSQ
AQAQAQTQTQ TQASQASQAQ IHTPNSGRGP QTPSTPGIDA LVEAAHIKRA EPSPSTAFPI
VPPAAAQHNT PTPRPSGYDG AAEPVADAPR RDFSSTCLSP EAQQTAAQLY SNIQKNHYAY
EDRVNFIRLL HQGFVDHIYP PASPDSHGDP HRFDVLKDLK AAREELDSLF AIGEDLWAEW
IQDESLLART VNERIAVMEL CRRSVEEEYG STKLWVIYGE WMLYLYKASA GDRDGSGRGH
WSDEDRIIGR EVFTWQSVVE VWKAGADATK WRINDCHLVW NRYLELLMQD VDASPSQERV
SQLRVLFESR LQTPHAGWDD TFQLFSNFVS KYYNANYEDL MVDARSKAAE AKAMYAARET
REAALHRTIE LKDTNAEWTT FQEYLDWELS KPQRRKGQQQ QQQQQQQLQP LRLELITSLY
QRAVLRFPTD ATLWEDYVMF LIDESMDGPM GVSPIPVIER ATRHCPWSGA LWSQLFISAE
RAGLSFAEIL ELKHKATRSG LLDAAGINEV LKVHTTWCSY LRRWALQPES TDEDLDVAEV
GIRSAIESVQ ELGDKTDKAV PNDPLFHLER IYIRYLSARG SWDSAREEFK HLIPRHGHSF
EFWLAYYTWE LLSWSKFMPC DSSASASRRM PNPSYATAVL KQALQRTDLD WPEKIMDAYI
SHCEHYEDAD ESQLAIIDVR KAMKALTKRR QREALQQQQQ QQQQQQQQQY HHHQQLANHQ
YHQVQDAAQH APVSAGAHLD SVEQQYHYPD ETQLAGKRKR EGEPEVNGTV SKRAKGGAIP
SVETRARDRE HASVIVKNLP KDIPQVKIRQ FFRDCGKLNS LQMLPGDSGS ALLEFDTHED
ALAAGTKNQK ILEGNQVTVE PVTDTTIFVT NFPPTADENY IRELFHSYGE IAEVRFPSLK
FNTHRRFCYV QFISSSSAYA ATELDKKDLG DGLELVVKIS DPSQRQARSG AYEEGREIYV
CNIPYKTTEG DLVELFTAYG DVESVRIPTK VNGDTRGFGF VTFATKDQST AALAMNEKTF
KGRELNVRLS TNTGAKRHQN TIVSRSESPA TNAQRNGTST ASPLPGSLPD GQSKGKGDRH
LRTLGLMNIP DTVNDTRIRA LAEPHGVLVK INLRPDHQGA IVEYADTNDA GKASLALEGY
EITPGRFIHV GSVKEMLQQK AEHKIDRIPI GKEKGKVSSA TTSGSGTTGC SKMMTQPSAP
IRRPNQSSGS GRRGGLGVKR GGSGIPSRDK PPGSTTNHHD DTDGQKSNQK QSEPTTTRNK
TNDDFRAMLS QPK
//
