ID F2SVQ0_TRIRC Unreviewed; 475 AA.
AC F2SVQ0;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Caspase family p10 domain-containing protein {ECO:0000259|PROSITE:PS50207};
GN ORFNames=TERG_06622 {ECO:0000313|EMBL:EGD90394.1};
OS Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559305 {ECO:0000313|EMBL:EGD90394.1, ECO:0000313|Proteomes:UP000008864};
RN [1] {ECO:0000313|Proteomes:UP000008864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC family. {ECO:0000256|ARBA:ARBA00010884}.
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DR EMBL; GG700655; EGD90394.1; -; Genomic_DNA.
DR RefSeq; XP_003232630.1; XM_003232582.1.
DR AlphaFoldDB; F2SVQ0; -.
DR STRING; 559305.F2SVQ0; -.
DR ESTHER; trirc-f2svq0; abh_upf0017.
DR GeneID; 10373716; -.
DR VEuPathDB; FungiDB:TERG_06622; -.
DR eggNOG; KOG1838; Eukaryota.
DR HOGENOM; CLU_032487_1_0_1; -.
DR InParanoid; F2SVQ0; -.
DR OMA; MMTTSWG; -.
DR OrthoDB; 1655372at2759; -.
DR Proteomes; UP000008864; Unassembled WGS sequence.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR012020; ABHD4.
DR InterPro; IPR002138; Pept_C14_p10.
DR PANTHER; PTHR10794; ABHYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10794:SF63; ALPHA_BETA HYDROLASE 1, ISOFORM A; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PIRSF; PIRSF005211; Ab_hydro_YheT; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS50207; CASPASE_P10; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008864}.
FT DOMAIN 388..468
FT /note="Caspase family p10"
FT /evidence="ECO:0000259|PROSITE:PS50207"
FT REGION 113..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..475
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 53819 MW; 5CC86DC8DA958997 CRC64;
MGILSWFLPN GRVSFHHAGK SVILKRKPQK KGPGVDESKY ISLADLCKSA TPADCQLNPF
LFNGHLQTAW TLMRTDDIPV YYKRWRFEGD SPDYRGSFEV DFVVPPYDVN KTSSSLTSEQ
SDNGTFESST PPDSTHPSPR TSFFTKEEFS ALPSDDKKPM LVVLHGLSGG SHEPYLRNIV
DPLHKQGWEV CVVNFRGCAN SKVTSSILYN ARATWDVRQT VRWLRKNFPF RPLFGIGFSL
GANILTNYVG EEGEDCQLKA AVVCSNPWNL EVSSLALQRT WVGLQIYSKT MGASMRRLFE
QHVDKLREHP RVNVERVRKT TYLHEFDREL QAPVWGYPTE TAYYRDASSI DSLFAVKIPL
FAIQAEDDAI SSKEALPYLE MTKTPYAVMC TTSWGGHLSW FEYGGGRWFT KPVVNFLNKM
VSEIDLDAPL TVVEEEMESK SNLNPAASPE RVDGPHPDFT PMRRKLHMPI PDGRE
//
