ID F2T0Q1_TRIRC Unreviewed; 314 AA.
AC F2T0Q1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Peripheral subunit-binding (PSBD) domain-containing protein {ECO:0000259|PROSITE:PS51826};
GN ORFNames=TERG_08388 {ECO:0000313|EMBL:EGD92173.1};
OS Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559305 {ECO:0000313|EMBL:EGD92173.1, ECO:0000313|Proteomes:UP000008864};
RN [1] {ECO:0000313|Proteomes:UP000008864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00007317}.
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DR EMBL; GG700661; EGD92173.1; -; Genomic_DNA.
DR RefSeq; XP_003231090.1; XM_003231042.1.
DR AlphaFoldDB; F2T0Q1; -.
DR STRING; 559305.F2T0Q1; -.
DR GeneID; 10377311; -.
DR VEuPathDB; FungiDB:TERG_08388; -.
DR eggNOG; KOG0557; Eukaryota.
DR HOGENOM; CLU_056413_0_0_1; -.
DR InParanoid; F2T0Q1; -.
DR OMA; DGIMMKI; -.
DR OrthoDB; 52212at2759; -.
DR Proteomes; UP000008864; Unassembled WGS sequence.
DR GO; GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; IEA:InterPro.
DR Gene3D; 4.10.320.10; E3-binding domain; 1.
DR InterPro; IPR045257; E2/Pdx1.
DR InterPro; IPR036625; E3-bd_dom_sf.
DR InterPro; IPR004167; PSBD.
DR PANTHER; PTHR23151; DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED; 1.
DR PANTHER; PTHR23151:SF82; PYRUVATE DEHYDROGENASE COMPLEX PROTEIN X COMPONENT, MITOCHONDRIAL; 1.
DR Pfam; PF02817; E3_binding; 1.
DR SUPFAM; SSF47005; Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex; 1.
DR PROSITE; PS51826; PSBD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008864}.
FT DOMAIN 38..78
FT /note="Peripheral subunit-binding (PSBD)"
FT /evidence="ECO:0000259|PROSITE:PS51826"
FT REGION 253..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 34052 MW; 3D2C1221ADE5B7E9 CRC64;
MANLSALARR LPLRQTSNGY YSVRCVQTAA QQPNSSYPLY PSVAQLLKQN NIPSNNVSKI
TATGPNGRIL KGDVLSYLGT IAASYPADLA SQLAKNSRLD LSNINIAAPQ APSPAASTLQ
EEQIQVEEET AGSRSEEAAG SVFETKIAVP VSFSKLISVR RRIQSSVGVE IPLATFVSRA
ADIANENLPV KPSEKQRSSA LFDEILGHRP CASTQMAFSR GDYLPEIVSP SEFYSSSGES
QQSLRKSTDD IIDVLTGRSP PSKRNVTRTA EAEEDRNTSI FSLTIPEHEE ARAMAFLEKM
QVLLEEEPAQ LLAL
//
