ID   F2TVQ6_SALR5            Unreviewed;       496 AA.
AC   F2TVQ6;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Translation initiation factor eIF2B subunit gamma {ECO:0000256|ARBA:ARBA00044196};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit gamma {ECO:0000256|ARBA:ARBA00044229};
GN   ORFNames=PTSG_00173 {ECO:0000313|EMBL:EGD72152.1};
OS   Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX   NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN   [1] {ECO:0000313|Proteomes:UP000007799}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "Annotation of Salpingoeca rosetta.";
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC       {ECO:0000256|ARBA:ARBA00007878}.
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DR   EMBL; GL832955; EGD72152.1; -; Genomic_DNA.
DR   RefSeq; XP_004998724.1; XM_004998667.1.
DR   AlphaFoldDB; F2TVQ6; -.
DR   STRING; 946362.F2TVQ6; -.
DR   EnsemblProtists; EGD72152; EGD72152; PTSG_00173.
DR   GeneID; 16067597; -.
DR   KEGG; sre:PTSG_00173; -.
DR   eggNOG; KOG1462; Eukaryota.
DR   InParanoid; F2TVQ6; -.
DR   OMA; NCVINPK; -.
DR   OrthoDB; 161736at2759; -.
DR   Proteomes; UP000007799; Unassembled WGS sequence.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR45989; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR   PANTHER; PTHR45989:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT   DOMAIN          7..144
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
FT   REGION          353..387
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   496 AA;  54163 MW;  3CBB0CCA7D432908 CRC64;
     MTSSFQPVVL AAGLGQGLQP LTKTYCKATL PIANVPMISY VLHLLNREGF PDAIIICRES
     HEDRIKATLT ASSEKKGPTK TSIVPYTIET IPDDSTMGTA DALRLFASKI QKDVLLLPCD
     LICNVPFSRL LDVHRLRDAS LTMLLARPSR DITAKKKTQH RATYQLDRDI IGLADDRVFI
     MTSETSAIEK TALQVSQHAG TQAGTITIRR DLEDPHVYIL KKWVVDMIAD RDLLSSIKDD
     LVPYLVSKQF APPRKHSKDI YNYIPASETA RYAGIVPSVK LDDRIRCHAL VLENVHGLNR
     PSPTANFCCT RVRTLEQYME INHGMHNFLQ DLLDVPEEQV QELQADLRTA LVTPNKQQQQ
     HGDDDDDDDA SGDGSKQAAT GAEGTTPRGI TVAKVAKVSK DVFVGVGSRA EPGATMHSCV
     IGDDCTIGEG TAIRGCVIMN NVSIGRNCLL TNVCVCDNAR IESNSRLSNC NVAPGHVVKP
     GTIRQGTVTG SAPSFI
//