ID F2U0M8_SALR5 Unreviewed; 491 AA.
AC F2U0M8;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=serine--tRNA ligase {ECO:0000256|ARBA:ARBA00012840};
DE EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
GN ORFNames=PTSG_01539 {ECO:0000313|EMBL:EGD80956.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832958; EGD80956.1; -; Genomic_DNA.
DR RefSeq; XP_004997517.1; XM_004997460.1.
DR AlphaFoldDB; F2U0M8; -.
DR STRING; 946362.F2U0M8; -.
DR EnsemblProtists; EGD80956; EGD80956; PTSG_01539.
DR GeneID; 16078114; -.
DR KEGG; sre:PTSG_01539; -.
DR eggNOG; KOG2509; Eukaryota.
DR InParanoid; F2U0M8; -.
DR OMA; EQNCIDR; -.
DR OrthoDB; 239638at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00770; SerRS_core; 1.
DR Gene3D; 1.10.287.40; Serine-tRNA synthetase, tRNA binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR InterPro; IPR015866; Ser-tRNA-synth_1_N.
DR InterPro; IPR042103; SerRS_1_N_sf.
DR InterPro; IPR033729; SerRS_core.
DR InterPro; IPR010978; tRNA-bd_arm.
DR NCBIfam; TIGR00414; serS; 1.
DR PANTHER; PTHR11778:SF7; SERINE--TRNA LIGASE, CYTOPLASMIC-RELATED; 1.
DR PANTHER; PTHR11778; SERYL-TRNA SYNTHETASE; 1.
DR Pfam; PF02403; Seryl_tRNA_N; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PIRSF; PIRSF001529; Ser-tRNA-synth_IIa; 1.
DR PRINTS; PR00981; TRNASYNTHSER.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46589; tRNA-binding arm; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT DOMAIN 196..475
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT COILED 78..122
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 491 AA; 54085 MW; 5DD4F6302BA605B3 CRC64;
MLALGFARKA CCSAAASAAA AAASGRVRLR LLSAAAAGVG GGTANIGPTS AATAPIRPSL
NFKGWRDNLE YHRANIRNRN VEANVDAAVE AYEQYVAQLQ RVEQLRHERN RLTDSIKKMK
DKKGSEFQEL LRQSKQNKTI LQEVESQMPW VEEAMLIEGL AIPNETHPDV PVGSEEQATV
LQTVNEAPSF CFEPRDHLAI AQPNNLINFR SGAAVTGSRF YFLHGKVALL EFALVHYAIN
FMTQRGYEPV TVPDIVKTRV AESCGFQPRD DASQIYHLDQ QHSVGQAELC LAGTAEIPLA
GMWMGHTFDD SELTKKYIAV GHAFRCEAGG AGATNRGLYR VHQFTKAELF VISPGDLETS
CGLHDEMLQD QIDLFASLGL HFKVLDMPTE DLGAPAYRKY DIEAWMPGRQ EFGEISSTSN
CTDYQSRRLN IRSRPTQAAP SSFVHTLNGT ACAVPRMIVA IMETFQREDG DFDIPAVLEP
YMPHGEGRKP T
//
