ID F2UEV3_SALR5 Unreviewed; 982 AA.
AC F2UEV3;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Glycoside hydrolase family 38 central domain-containing protein {ECO:0000259|SMART:SM00872};
GN ORFNames=PTSG_06807 {ECO:0000313|EMBL:EGD75153.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; GL832971; EGD75153.1; -; Genomic_DNA.
DR RefSeq; XP_004992206.1; XM_004992149.1.
DR AlphaFoldDB; F2UEV3; -.
DR EnsemblProtists; EGD75153; EGD75153; PTSG_06807.
DR GeneID; 16072765; -.
DR KEGG; sre:PTSG_06807; -.
DR eggNOG; KOG1959; Eukaryota.
DR InParanoid; F2UEV3; -.
DR OMA; WRQNWDM; -.
DR OrthoDB; 5474711at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd00451; GH38N_AMII_euk; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF3; LYSOSOMAL ALPHA-MANNOSIDASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 351..440
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
FT REGION 573..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 982 AA; 106671 MW; F9739B89B541E687 CRC64;
MAQLKQLHSG RGIPSLRFIV GTCLLIAAAT TLLASAENVQ VHLIPHSHQD PGYRETVYGY
WRDSVSDTLR TTVQALQDDP TRRFVWEETI WLRYLWESGD ADTINGIQHL VKNGQLELIG
GGWVMHDEAG SSLWSTANQM TIGLDFLFDK FKTRPKWAWH IDPFGHSVTS PSVFASLGYS
AFVINRIPDD EKQERKANRS LELLWTGSTA QHPDSTLLAH VLDSHYATPV LPGVTAAEKA
KQLAEQCAQR AKWYRTKHVL VPFGNDFEFK DARLQFDAMD EILRIINNDP ASHSNVTIKY
STLNEYFTAL HADPNAVFPA AAPGKDFFPY IACSPCTASK CIGLPCGSRD AYWVGYYTSR
PHQKLMSFKQ DALARSLNIL QTLQRHATTT DTTATTSTTG VADADLVVTT ARNTSGLMQH
HDALPGTSFN YCTISTSECD CVADYNKRIA AAAQSSDNLI GNIEAKLLGV PGNVSVVTAA
TLANSSYSSP EWTIFISNPV AWRRRDVVQV DIAGVTTSRV INVKTGEIVP SQVVVDPLRG
KNFVYIAVDL PPLAIATYRL ELGVVDPQQQ QQESSSSSSF FSSSSSSSSS SLCNGAVCIT
FSSTTGRPTA WVDLASGTTH ALNVDHVYMR ERTPVDADIF SGSNVYDFTP DGTSTSLWPA
RPTLVSVANG PIVWEQTATL SGDMYVSFRL YNASLVDETQ RSLQVQTHTG VMTSASSGSM
LMRVSTDVKS GTAFFTDNNA FQRKHRTFDS SLPYSGNFYP VVGAAIVTDA NTTARPRAHR
DSDSGGFALS LAASRPTAVT SPASGALEMM LHRRIMDLDL RGNDSSVMDD VVLVTLAPAS
VVQARAAKMS TLHLLPVTVH AVSGRVTPKV ATFAPMPKAL PDGVHLLDVR LRGSGFDEGV
GMWLQGLAGL DGGKVDPSEV LPCLSTRDWE RTSLDFRLSI NETRSARLKW KSDSSTADGQ
EGHAAATAAV NVKPESFLAF AS
//
