ID F2UP34_SALR5 Unreviewed; 802 AA.
AC F2UP34;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 28-JUN-2023, entry version 34.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
GN ORFNames=PTSG_12924 {ECO:0000313|EMBL:EGD79389.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832985; EGD79389.1; -; Genomic_DNA.
DR RefSeq; XP_004989158.1; XM_004989101.1.
DR AlphaFoldDB; F2UP34; -.
DR EnsemblProtists; EGD79389; EGD79389; PTSG_12924.
DR GeneID; 16069700; -.
DR KEGG; sre:PTSG_12924; -.
DR InParanoid; F2UP34; -.
DR OrthoDB; 5700461at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR CDD; cd00173; SH2; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..802
FT /note="SH2 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003291288"
FT DOMAIN 174..261
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 97..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..398
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..441
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..692
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..757
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 87323 MW; B03E9CD5983EAAF2 CRC64;
MPWRCWCVDK HEDGVLCCAF ALCWLARFTS SSQQPAAASH QPYISFVLSL THTHNGGDTA
TEVTTSTTVA HTHTHTRTHT HTHTHNAAML KMLKLRKRPQ QHTSTDGKKE QHKEADTTKQ
QQQQQQHQQQ QVVRDTNPEE QQRRGRQRAA SLGSPAQRAL PKIPSVEEQQ ENQAYHVGVC
SRTEANQRLA VCRDGTFLVR RSPTDGGYVF SVIWRDNPGK LGTFTHAKIV PATKDKGMFA
LADVDAFVTM DELVRFYQRS PVIFAMRFWP DAEGVSLPDF FAYDKFNPHI NSKHEHVRSR
AASHMSAQDS SGGASDTANN DSSDTSGSAN NVTGSANSNS NTFADDTKST SNNTATVATV
AISSSAADER KYMTASPARL DAMFPSPSSS SSPSSSPAAA LHAPRPRRVR HQTQEDAEAA
RRMSEGHVGR RGHHHHHNRH HRGVDGDGER RRGSSPASAG VSSSPATAAA AAVACKHGDK
KRAEKKEKKE KKKKKKGRKS KEEGEEQDSH NLKLHLPDLE LLKANLPKSD SFVESGSHPS
WASNARRMEF RPVIPPRSRS NTPQSNLPHV PLRSHAPSPA PPSATPPSNA NTTATNTDNN
TTTSVLERDD SSDPYEEAQP ADELLPPTPS SSSSSPSSSA MANGGGAGEN LQRPTPTRSA
AVYETPVCKS PIPSSLGAPP PPPPPLRNSR SPQPPTLPSA TTASTTAPAS PLQRSHQPSP
QQQQQQQQQQ QQQQQNSSPF SRDSIVITPS ALRQNRRPTD QYRPVEASRP LYESAYQCVL
TVKDGKSSPL SSMESSSGHT QL
//
