ID F2UTK9_SALR5 Unreviewed; 285 AA.
AC F2UTK9;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN ORFNames=PTSG_11480 {ECO:0000313|EMBL:EGD72982.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL833060; EGD72982.1; -; Genomic_DNA.
DR RefSeq; XP_004987494.1; XM_004987437.1.
DR AlphaFoldDB; F2UTK9; -.
DR STRING; 946362.F2UTK9; -.
DR EnsemblProtists; EGD72982; EGD72982; PTSG_11480.
DR GeneID; 16068014; -.
DR KEGG; sre:PTSG_11480; -.
DR eggNOG; KOG0941; Eukaryota.
DR InParanoid; F2UTK9; -.
DR OMA; HIVPCDQ; -.
DR OrthoDB; 5471864at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700:SF8; HECT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 1..285
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT ACT_SITE 253
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 285 AA; 32204 MW; C85327E63998A7D7 CRC64;
MFKPIAGNTL IWINAHTHEP LRSFYYFGVL VGLALYNSVN IRLNLPLAFY KQLLDRRADA
SDFRAMFPDL AHGLDQLLEY PGDVETDICS TYSVSDMYLG EAIEQPLIEG GNDIVVTNET
RQQYVKDYIE FVLHKSMEQQ MGAIRNGFMA VMAGWAVNLC TPAELQVMIC GRDDIDLSTM
KPSAAYIGYE ESDDTIQHLW RFLDSLDDEG KRNFLLFVSG SARVPLGGLQ SLHFTIQRAE
HTNFSRLPTA MTCFNRLVLP AYPTEELLRQ RVQTAIDNAQ GFGLV
//
