ID   F2VJM9_HYPNO            Unreviewed;       286 AA.
AC   F2VJM9;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Homeodomain protein HoxA1a {ECO:0000313|EMBL:ADZ74204.1};
DE   Flags: Fragment;
GN   Name=hoxa1a {ECO:0000313|EMBL:ADZ74204.1};
OS   Hypophthalmichthys nobilis (Bighead carp) (Aristichthys nobilis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Xenocyprididae; Xenocypridinae; Hypophthalmichthys.
OX   NCBI_TaxID=7965 {ECO:0000313|EMBL:ADZ74204.1};
RN   [1] {ECO:0000313|EMBL:ADZ74204.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=20976012; DOI=10.1371/journal.pone.0013508;
RA   Tao W., Zou M., Wang X., Gan X., Mayden R.L., He S.;
RT   "Phylogenomic analysis resolves the formerly intractable adaptive
RT   diversification of the endemic clade of east Asian Cyprinidae
RT   (Cypriniformes).";
RL   PLoS ONE 5:E13508-E13508(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR   EMBL; GU218207; ADZ74204.1; -; Genomic_DNA.
DR   AlphaFoldDB; F2VJM9; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   InterPro; IPR046327; HXA1/B1/D1.
DR   PANTHER; PTHR45946:SF3; HOMEOBOX PROTEIN HOX-A1; 1.
DR   PANTHER; PTHR45946; HOMEOBOX PROTEIN ROUGH-RELATED; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}.
FT   DOMAIN          204..264
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        206..265
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          35..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          258..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADZ74204.1"
FT   NON_TER         286
FT                   /evidence="ECO:0000313|EMBL:ADZ74204.1"
SQ   SEQUENCE   286 AA;  31513 MW;  81A51D7775F3A8F8 CRC64;
     SSCSVRAFHG DHGLSTFQSS CAVRVNSCSG DERFMSNRSS QDAINPQPHQ AGSFQSPGTL
     SITYSAHPSY GTQSFCSGYS HYALNQDVDS SVSFPQCGPL IYSGNISSTV VQHRHHRHGY
     SSGNVHLHGQ FQYASATYGN SPDQANLTFV AGCSNPLSPL HVAHHDACCS PLSDGVSTGQ
     TFDWMKVKRN PPKTGKAGEY GFGGQPNTVR TNFTTKQLTE LEKEFHFNKY LTRARRVEIA
     AALQLNETHV KIWFQNRRMK QKKREKEGLL PKSPSELKDG LGKNNE
//