ID   F3ADU7_9FIRM            Unreviewed;       626 AA.
AC   F3ADU7;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Polysaccharide biosynthesis protein CapD-like domain-containing protein {ECO:0000259|Pfam:PF02719};
GN   ORFNames=HMPREF0992_01242 {ECO:0000313|EMBL:EGG84131.1};
OS   Lachnospiraceae bacterium 6_1_63FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658083 {ECO:0000313|EMBL:EGG84131.1, ECO:0000313|Proteomes:UP000004368};
RN   [1] {ECO:0000313|EMBL:EGG84131.1, ECO:0000313|Proteomes:UP000004368}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=6_1_63FAA {ECO:0000313|EMBL:EGG84131.1,
RC   ECO:0000313|Proteomes:UP000004368};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA   Yandava C., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 6_1_63FAA.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG84131.1}.
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DR   EMBL; ACTV01000012; EGG84131.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3ADU7; -.
DR   HOGENOM; CLU_013560_5_2_9; -.
DR   Proteomes; UP000004368; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          301..581
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   626 AA;  71542 MW;  F3F61CEF4B7F081D CRC64;
     MEQNIKEKKL LDLQWVRRAL LLLLGDITII IMASIGALIA RFDFSYNSID AIYLESMYRY
     LPIHILTTVL IFYFCKMYHS LWKFISIHEL GYIILANIVS FFMQIAGFHL MQYPIPRSYF
     FLEILLQTVM VVGIRFSYRF CRYLKEAREQ RFGCGEPQKR VMIIGAGDAG RAIIKEILDS
     RHLTMKVCCV IDDDCNKEGR YINGIPIIGD RSVILKNVEK YKIDKIILAI PSASKEERRE
     ILEICKMTKC ELKTLPGMYQ LIDGELNIGK LRDVEITDLL GRDPIQVNLD EIMGYVEQKI
     IMVTGGGGSI GSELCRQIAM YNPKQLIIFD VYENNAYEIQ QELKRHHPEL NLVVLIGSVR
     NTHRMETVFE KYRPDIVYHA AAHKHVPLME DSPNEAIKNN VFGTYKIAKA ASEYGVKRFV
     LISTDKAVNP TNIMGASKRL CEMIVQSFDK ISKTEFVAVR FGNVLGSNGS VIPLFKKQIA
     EGGPVTVTHK DIIRYFMTIP EAVSLVLQAG AYARGGEIFV LEMGAPVRID DMARNLIRLS
     GYTPDVDIKI EYTGLRPGEK LYEELLMAEE GMKETANKLI HIGKPIEMDE ETFFDKLAEL
     KEACYNDDES IKEKVQKLVP TYRIKK
//