ID F3B067_9FIRM Unreviewed; 829 AA.
AC F3B067;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Clp R domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF0491_00431 {ECO:0000313|EMBL:EGG91250.1};
OS Lachnospiraceae oral taxon 107 str. F0167.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=575593 {ECO:0000313|EMBL:EGG91250.1, ECO:0000313|Proteomes:UP000003263};
RN [1] {ECO:0000313|EMBL:EGG91250.1, ECO:0000313|Proteomes:UP000003263}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0167 {ECO:0000313|EMBL:EGG91250.1,
RC ECO:0000313|Proteomes:UP000003263};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Baranova O.V.,
RA Blanton J.M., Tanner A.C., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium oral taxon 107 strain
RT F0167.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG91250.1}.
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DR EMBL; ADDS01000004; EGG91250.1; -; Genomic_DNA.
DR AlphaFoldDB; F3B067; -.
DR STRING; 575593.HMPREF0491_00431; -.
DR eggNOG; COG0542; Bacteria.
DR HOGENOM; CLU_005070_4_1_9; -.
DR OrthoDB; 9803641at2; -.
DR BioCyc; LORA575593-HMP:GMJL-432-MONOMER; -.
DR Proteomes; UP000003263; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000003263};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..145
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 422..457
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 418..464
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 829 AA; 93433 MW; 9F6E6F5D979BC459 CRC64;
MAERYTSQAK EAIKYAEMAA KELSQNYVGT EHLLLGLVQE GSGVAAKILE NNGITEEKIL
NLIDQLIVSN YNVAIESKQN YSPLAIGVLQ NAYREATRYK SALIGTEHIL IAIIKDSACI
AHKLLLTMNI NIQRIYMEIL SAMGEETERK ENYEKTSNKS ASLSTPTLDK YSRDLTEFAR
IGKLDPVIGR DNETNRVMQI LSRRTKNNPV LIGEPGVGKT AVVEGLASRI ISKEVPDTLL
DKRLVTLDLP AMIAGSKYRG EFEERIKKVI NEVVSAGNVL LFLDELHTII GAGGAEGAVD
ASNILKPLLA RGELQLIGAT TIDEYRKHIE KDSALERRFQ PIIVEEPSLE DATKILMGLK
HKYEEHHAVS ITDRAIESAV KLSKRYISDR FLPDKAIDLV DEAASKTRIS NYMEPEKIKE
IKAEIEKMEK EKEDAVGAEE FEKAGEIKEK QEKLREKQNK LREKWIEDKK NKKLIVDEDE
IADVVALWTK IPVKKITEND SQRLNNLEKV LHERVVGQEE AVNAVARAIR RGRVGLKDPK
RPIGSFLFLG PTGVGKTELS KALAYSMFGS ENALIRVDMS EYMEKHSVSK MVGSPPGYVG
YDEGGQLSEK VRRNPYSVIL FDEIEKAHPD VFNILLQVLD DGHITDSSGR TVDFKNTVII
LTSNAGAQRI VEPKQLGFAS NSDNEKDYSV MKTNVMDEVK QMFKPEFLNR IDETIVFHQL
TRENLKEILD ILLKEINNRL LEQMQMSLKL TEKAKEFLID KGYDKKYGAR PLKRALQNEI
EDKMAEEILA GNVKQGDSLK VDCKGEDKER ELIFKPVVKK TKTKELITQ
//
