ID   F3B140_9FIRM            Unreviewed;       621 AA.
AC   F3B140;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=Rad50/SbcC-type AAA domain-containing protein {ECO:0000259|Pfam:PF13476};
GN   ORFNames=HMPREF0491_00742 {ECO:0000313|EMBL:EGG89612.1};
OS   Lachnospiraceae oral taxon 107 str. F0167.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=575593 {ECO:0000313|EMBL:EGG89612.1, ECO:0000313|Proteomes:UP000003263};
RN   [1] {ECO:0000313|EMBL:EGG89612.1, ECO:0000313|Proteomes:UP000003263}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0167 {ECO:0000313|EMBL:EGG89612.1,
RC   ECO:0000313|Proteomes:UP000003263};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Baranova O.V.,
RA   Blanton J.M., Tanner A.C., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA   Yandava C., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium oral taxon 107 strain
RT   F0167.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG89612.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ADDS01000006; EGG89612.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3B140; -.
DR   STRING; 575593.HMPREF0491_00742; -.
DR   eggNOG; COG4717; Bacteria.
DR   HOGENOM; CLU_018670_0_0_9; -.
DR   OrthoDB; 9764467at2; -.
DR   BioCyc; LORA575593-HMP:GMJL-752-MONOMER; -.
DR   Proteomes; UP000003263; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   PANTHER; PTHR41259:SF1; AAA_27 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR41259; DOUBLE-STRAND BREAK REPAIR RAD50 ATPASE, PUTATIVE-RELATED; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003263};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        294..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          5..245
FT                   /note="Rad50/SbcC-type AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13476"
FT   COILED          403..461
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   621 AA;  70075 MW;  CEE96ED5E68BF57D CRC64;
     MKLLSLHIDG FGKFKNKDLQ FSDNMNIIYG YNEAGKSTIF MFIKAMFYGL ERAKGRASKS
     DTWTKFKPWG NGDIYGGNLR FLYHEKAYRI ERDFTKTATT PFNIVNETDG KNVENPAVFL
     KEALCGLTET AYSNTVSISQ LKSATDAKMV VELKNYIANM NTTGNMSLNI TKASEFLKEK
     KKAFVASLNP DAAKTYNQNL TEIRALEKKI ASPEFSSHLK TLKEADAITD KRIIELNSQR
     ESLIESIASK RQHLSDLGFT DKRNIISLQN ELNRGYNDYL SAYETEKKSI SKTYSAVFLI
     LAIVSVILAI YIFKSGKNNV FTTTTGISFQ FAMVLFMIIG LASLIFASYI YTVHNKDNRH
     LTELKVNLIA LMARVGSFDS ITEDNIHRAN KTLNSKLVIF DEMAADIAKS EALNEDIENL
     RAKKAAYASG IDAKKQNEWE LEKLMEKLAH MKEDNASLKN VILENDKIRF EIDAIDLAME
     TLKNLSETIK NSFGLYLNKD ASELIEGITG GVYDSISIDE NFNVFLNTPS RLVPIEQASS
     GTMDQVYLAL RIAAGRLMQG RAKELPFIFD DSFVNYDSIR LRAALLWIAN NVPEQIIVFS
     CHMREAQLMT ATMQDFNLIE L
//