ID   F3B8X5_9FIRM            Unreviewed;       250 AA.
AC   F3B8X5;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   RecName: Full=PurE domain-containing protein {ECO:0000259|SMART:SM01001};
GN   ORFNames=HMPREF9477_00395 {ECO:0000313|EMBL:EGG84996.1};
OS   Lachnospiraceae bacterium 2_1_46FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=742723 {ECO:0000313|EMBL:EGG84996.1, ECO:0000313|Proteomes:UP000018451};
RN   [1] {ECO:0000313|EMBL:EGG84996.1, ECO:0000313|Proteomes:UP000018451}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2_1_46FAA {ECO:0000313|EMBL:EGG84996.1,
RC   ECO:0000313|Proteomes:UP000018451};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 2_1_46FAA.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG84996.1}.
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DR   EMBL; ADLB02000007; EGG84996.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3B8X5; -.
DR   STRING; 742723.HMPREF9477_00395; -.
DR   eggNOG; COG1691; Bacteria.
DR   HOGENOM; CLU_065705_0_0_9; -.
DR   OrthoDB; 9782511at2; -.
DR   Proteomes; UP000018451; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   InterPro; IPR039476; P2CMN_synthase_LarB.
DR   InterPro; IPR000031; PurE_dom.
DR   NCBIfam; NF033503; LarB; 1.
DR   PANTHER; PTHR43064; PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE-RELATED; 1.
DR   PANTHER; PTHR43064:SF1; SLL1489 PROTEIN; 1.
DR   Pfam; PF00731; AIRC; 1.
DR   SMART; SM01001; AIRC; 1.
DR   SUPFAM; SSF52255; N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE); 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018451}.
FT   DOMAIN          115..246
FT                   /note="PurE"
FT                   /evidence="ECO:0000259|SMART:SM01001"
SQ   SEQUENCE   250 AA;  27012 MW;  D31AE7682DF824A2 CRC64;
     MDTKKILEQV KNGAMSVEEA EEFFRRQPFE DLGYAKLDTH RKLRSGCAEV VFCSGKADEH
     LLSIYERLYA EEGEVLGTRA SKEQAELVQS KLPEVEYDAL SRILKIEKKE KEYVGKIVVC
     TAGTADIPVA EEAAQTAEFF GNHVERIYDV GVSGLHRLLS RVETIQSANC VITVAGMEGA
     LASVIGGLVD KPVIAVPTSV GYGASMNGIS ALLTMINSCA NGIATVNIDN GYGAGYIASQ
     INKLGVHEHE
//