ID   F3B970_9FIRM            Unreviewed;       769 AA.
AC   F3B970;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Phage/plasmid primase, P4 family domain-containing protein {ECO:0000313|EMBL:EGG84920.1};
GN   ORFNames=HMPREF9477_00647 {ECO:0000313|EMBL:EGG84920.1};
OS   Lachnospiraceae bacterium 2_1_46FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=742723 {ECO:0000313|EMBL:EGG84920.1, ECO:0000313|Proteomes:UP000018451};
RN   [1] {ECO:0000313|EMBL:EGG84920.1, ECO:0000313|Proteomes:UP000018451}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2_1_46FAA {ECO:0000313|EMBL:EGG84920.1,
RC   ECO:0000313|Proteomes:UP000018451};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 2_1_46FAA.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG84920.1}.
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DR   EMBL; ADLB02000007; EGG84920.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3B970; -.
DR   STRING; 742723.HMPREF9477_00647; -.
DR   eggNOG; COG3378; Bacteria.
DR   eggNOG; COG4983; Bacteria.
DR   HOGENOM; CLU_018483_1_1_9; -.
DR   OrthoDB; 9763644at2; -.
DR   Proteomes; UP000018451; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004968; DNA_primase/NTPase_C.
DR   InterPro; IPR006500; Helicase_put_C_phage/plasmid.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR01613; primase_Cterm; 1.
DR   PANTHER; PTHR35372; ATP BINDING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35372:SF2; SF3 HELICASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF03288; Pox_D5; 1.
DR   SMART; SM00885; D5_N; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018451}.
FT   DOMAIN          478..641
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000259|PROSITE:PS51206"
SQ   SEQUENCE   769 AA;  88178 MW;  5A1CBE030BCF7183 CRC64;
     MYEKLPEELK KDGRFCLWKY EERNGRITKV PYQINGKKAS SADKNTFSDF RMAVNAMDDY
     DGIGMGAFDD FCMVDIDHCV CGGKLTRMAE NIIEKMDSYT EISPSGTGVR IVCKASSLFY
     DKGRYYINNS KIGLEIYVSD VTKKFCTLTG NAIRNCGVEE RSGQLGIILE TYMLRPIPKE
     KDREQDIPGS YLSDDSVVRL ASDSRQGRKF KSLWNGEIPE GKSHSDADMS LASILAFWCG
     GDLEQMDRLF RKSGLMRSKW DRVQSGSTYG ALTLEKAVAQ AVEFYRPYAT TSAESDFDDM
     LQKLVEWNVS DNRRYPWNDN GSGRLFADVY KDIARYVPER KKWYVYDGTR WIPDIGGLKT
     MELAKSLADT LVRYALTIAD ERRRKDYLEY SAKWQSRNYR NTYISDAQSV YPIAMSEFDR
     NIYYLNCQNG TLDLQTGEFH LHTPQDKLTK IAGAAYDPNA KSPRFIRFIS EVMSGDKEKV
     RFMQKSLGYG LTGDTRYECM FFYYGATTRN GKGTLMESTL HVMGDYGLTV RPETIAAKPS
     VNSQNPTEDI ARLAGIRFAN ISEPRRGLVL NEAQIKSMTG NDTLNARFLH ENSFDFKPQF
     KLYVNTNYLP AITDMTLFSS GRIVIIPFDR RFEEWEQEQN LKAEFSKPEI ASAILNWLIE
     GYTLLQEEGF DQPTAVKDAI LSYQHDSDKM QLFVEEFLEK EKDAECRTSA VYQAYRNWCN
     NNGYFAENSR NFNQALRTIG MVVRKRPKDG GEKTTLLTGY RLLCRDFLC
//