ID F3P742_9ACTO Unreviewed; 1146 AA.
AC F3P742;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Exonuclease SbcCD, C subunit {ECO:0000313|EMBL:EGF56388.1};
GN ORFNames=HMPREF9056_00856 {ECO:0000313|EMBL:EGF56388.1};
OS Actinomyces sp. oral taxon 170 str. F0386.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=762963 {ECO:0000313|EMBL:EGF56388.1, ECO:0000313|Proteomes:UP000004404};
RN [1] {ECO:0000313|EMBL:EGF56388.1, ECO:0000313|Proteomes:UP000004404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0386 {ECO:0000313|EMBL:EGF56388.1,
RC ECO:0000313|Proteomes:UP000004404};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF56388.1}.
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DR EMBL; AFBL01000021; EGF56388.1; -; Genomic_DNA.
DR RefSeq; WP_009402857.1; NZ_GL882522.1.
DR AlphaFoldDB; F3P742; -.
DR STRING; 762963.HMPREF9056_00856; -.
DR eggNOG; COG0419; Bacteria.
DR HOGENOM; CLU_004785_2_0_11; -.
DR OrthoDB; 9795626at2; -.
DR Proteomes; UP000004404; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR32114; ABC TRANSPORTER ABCH.3; 1.
DR PANTHER; PTHR32114:SF2; ABC TRANSPORTER ABCH.3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exonuclease {ECO:0000313|EMBL:EGF56388.1};
KW Hydrolase {ECO:0000313|EMBL:EGF56388.1};
KW Nuclease {ECO:0000313|EMBL:EGF56388.1}.
FT DOMAIN 5..181
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT REGION 222..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 331..382
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 545..613
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 827..854
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 688..725
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1146 AA; 121907 MW; 0ED13663E3132B35 CRC64;
MRIHSLTMTG IGPYAGREHV DFDAVGASGR FLLTGPTGSG KTTIIDAIVF ALYGDVADSA
DSSKERIRST LVGPHTESVI ELVFSTGAGV YRVRRTPTYE RAKRSGQGTT AQNATVKLWH
LAEVGGEPFD EPVTRVGDAD AEIARAVGLS REQFTQTVVL PQGKFARFLR ADSSERQQLL
KDVFGTGIYD AIQDALIQAS RDGARQVEQA AADLRGQVAS LRRHPLLTEA PSPAETTDTG
EEADDADHAT LQDDSSQEAP PGGTREALPL LMEDADHDEP EEADAGPTPT PAQALEAAMV
GTTPDLVALR RVGAEVLDVS RNRAQQADAR AEAAGKVLAR AQAAREEAQR LHDLLGRRRA
LVEEDQRLAE RAEQDADNAA RLQAAERAAR VRPYLTAEQA ARGRAQQAVA ALAARADQSG
LAHLAEQAGD TSPGSTEEAT GSDAHSHGAA LTPAALVEPL VREAQHQFTA LEADPSEARA
GDTEASAAPQ DSDTAETPVA ADESETARAE ALSPRSLDDL AHRCRREHGQ LEALVDLEAG
LPSRESALQQ REAELQRAAT QLEQRAEKLA ERPAQRTALV EKLEAARAAR ERLDGLQDRR
AQAEERHRAA LAVEQLSTQL TQQDAACTQA AALAQEATER VRATRLAWIS GTAGTLAGEL
TEGEPCPVCG SPTHPSPASA DAEGATRQQV EAAEERQRQA DEALSGAVRE RDACAAQREE
AQRSSDGLDA TAAKAALDEA TTALTAAQAA ADGVDELAER LEAFDADTEQ ERTALDATRS
AQESARSRLE ADREALAQDQ RRCLEARGSW PSVTARAAAL LVRAGEAEDA SEDVEAARTA
LAQARSTLTD LTEALNEEDF TSAAQARAAS LDRGAIEDLT ATVSTAATAR ERVRLGLEDP
EIAALSGQEE DRLEDTSAEL ARADAAARQA ASLQARTAES HEHLRRAVDG VEQATTAYEE
AAGSSADLIR VASLARGENE TGIPLATWVL QARFEEVLVF ANERLSQMSS GRYELIRVTE
ETSQRRRRKG LGLAVVDHLG DERTRDPRTL SGGETFYVSL SLALALADVV SAESGGVSLE
TLFIDEGFGT LDADTLQTVM AEIDHLRAGG RTVGIVSHVA ELRDQIAEHI AVRRVASGGS
TLKVTA
//
