ID F3PB16_9ACTO Unreviewed; 568 AA.
AC F3PB16;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=ImpB/MucB/SamB family protein {ECO:0000313|EMBL:EGF53658.1};
GN ORFNames=HMPREF9056_02150 {ECO:0000313|EMBL:EGF53658.1};
OS Actinomyces sp. oral taxon 170 str. F0386.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=762963 {ECO:0000313|EMBL:EGF53658.1, ECO:0000313|Proteomes:UP000004404};
RN [1] {ECO:0000313|EMBL:EGF53658.1, ECO:0000313|Proteomes:UP000004404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0386 {ECO:0000313|EMBL:EGF53658.1,
RC ECO:0000313|Proteomes:UP000004404};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Poorly processive, error-prone DNA polymerase involved in
CC untargeted mutagenesis. Copies undamaged DNA at stalled replication
CC forks, which arise in vivo from mismatched or misaligned primer ends.
CC These misaligned primers can be extended by PolIV. Exhibits no 3'-5'
CC exonuclease (proofreading) activity. May be involved in translesional
CC synthesis, in conjunction with the beta clamp from PolIII.
CC {ECO:0000256|ARBA:ARBA00025589}.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF53658.1}.
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DR EMBL; AFBL01000053; EGF53658.1; -; Genomic_DNA.
DR RefSeq; WP_009404667.1; NZ_GL882544.1.
DR AlphaFoldDB; F3PB16; -.
DR STRING; 762963.HMPREF9056_02150; -.
DR eggNOG; COG0389; Bacteria.
DR HOGENOM; CLU_026357_0_0_11; -.
DR OrthoDB; 5244088at2; -.
DR Proteomes; UP000004404; Unassembled WGS sequence.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd03468; PolY_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR35369:SF2; BLR3025 PROTEIN; 1.
DR PANTHER; PTHR35369; BLR3025 PROTEIN-RELATED; 1.
DR Pfam; PF00817; IMS; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
FT DOMAIN 49..180
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 437..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 60328 MW; D3F6F84CE8693F59 CRC64;
MSRSQPSLPP GLPAARLVAI WVPDWPVVAL TMEARRQRRH HRAHQSDLRL LDPATEPVAV
VGVRGVLAAS APARSAGITT GMRLRAARSL CPGLTVLPPQ EEREGRAFET VMEALTSLLA
EPIVARPGLA LSGAKGPATW AGGEELLAAA LVEAVAQEAD TECQVGIADS LSGAVLAARQ
GIIVKPGQTP DFLAPWPLEA LLACLPLRRL RREARPLLET FTRLGLRTLA DLASLPRKDV
VARFGPMGER LHHLAAGTHH EAPAMTRPAQ DITVTSDLDP PVERADTAAF AARHLAENLV
TRLLSQGLAV GCLCVQARCE DGADLARTWM LETTPTTAEL ADRVRWQLEG WLSGRSGRPP
SSGLTHLSLT ALELSPATTS QTGLWQAPGQ QTQARAHRAA ERVESLIGAG TVQIPTVVPG
RDPRSRVRLI FWGEEERVGE PSGGASAPWS GSLPEPSPSI ILPRPVPVRL TDAQGCELGV
DIHGQLDGVP GFLAIGDDAE EGGGVIGGGA NGGGLESVLA WAGPWPVDEG WWTPQGPSRR
AYLQVVTDVG PPRLLVRSGR WWLDAVYS
//
