ID F3PXQ8_9BACE Unreviewed; 495 AA.
AC F3PXQ8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:EGF51640.1};
GN ORFNames=HMPREF9446_03556 {ECO:0000313|EMBL:EGF51640.1};
OS Bacteroides fluxus YIT 12057.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=763034 {ECO:0000313|EMBL:EGF51640.1, ECO:0000313|Proteomes:UP000003416};
RN [1] {ECO:0000313|EMBL:EGF51640.1, ECO:0000313|Proteomes:UP000003416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12057 {ECO:0000313|EMBL:EGF51640.1,
RC ECO:0000313|Proteomes:UP000003416};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF51640.1}.
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DR EMBL; AFBN01000099; EGF51640.1; -; Genomic_DNA.
DR AlphaFoldDB; F3PXQ8; -.
DR STRING; 763034.HMPREF9446_03556; -.
DR eggNOG; COG3669; Bacteria.
DR HOGENOM; CLU_002934_1_1_10; -.
DR Proteomes; UP000003416; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR031919; Fucosidase_C.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR Pfam; PF16757; Fucosidase_C; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003416};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..495
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003300405"
FT DOMAIN 415..492
FT /note="Alpha-L-fucosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16757"
FT SITE 297
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 495 AA; 57513 MW; 845048CA50214A30 CRC64;
MMKKAMLVFA ALFLMMGASA QDKTYEQTWE SLDSRPTPSW FKDAKFGIFI HWGIYSVPMW
SPKGTYQEWY KYWLDNKKLF GNGDFTGTEI YDYHTKMYGE DFNYNEFARK FKALDYDADA
WAKLFEKAGA KYIVLTTKHH DGYALWPSKE ASRDYGRPWN SVEVGPKRDL VKEYTDALRK
TDIKVGFYIS CREWESPLYK PELLDLYVSR HFIPQVKDLV NSYHPDLLWS DGPDNYSDSI
WQTKKLFQWI YSESPVKNTI VLNDRWARFT DGKKHGDYYT REYSTHAMPG DKPWEECRGM
GFSFSYNLNE DVEDYSSPQG LILTLVNIVS KGGNLLLGIG PNGSGKIPPI MQERLLQMGE
WLKVNGEAIY GTHAWKQTEQ WSKGDRNWKD KSKHYVGGNS ILKQTVDPDP GYAVKEIFFT
AKENSVYAIL PKLPEGKVIL KDVQSTRKTK VTMLGYDKKL QWKQNGKNLV IEVPVISYNE
VPCHYAWTLK LENVE
//
