ID F3QR57_9BACT Unreviewed; 737 AA.
AC F3QR57;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=RelA/SpoT family protein {ECO:0000313|EMBL:EGG56311.1};
GN ORFNames=HMPREF9442_00656 {ECO:0000313|EMBL:EGG56311.1};
OS Paraprevotella xylaniphila YIT 11841.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Paraprevotella.
OX NCBI_TaxID=762982 {ECO:0000313|EMBL:EGG56311.1, ECO:0000313|Proteomes:UP000005546};
RN [1] {ECO:0000313|EMBL:EGG56311.1, ECO:0000313|Proteomes:UP000005546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 11841 {ECO:0000313|EMBL:EGG56311.1,
RC ECO:0000313|Proteomes:UP000005546};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate)
CC is a mediator of the stringent response that coordinates a variety of
CC cellular activities in response to changes in nutritional abundance.
CC {ECO:0000256|RuleBase:RU003847}.
CC -!- SIMILARITY: Belongs to the relA/spoT family.
CC {ECO:0000256|RuleBase:RU003847}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG56311.1}.
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DR EMBL; AFBR01000020; EGG56311.1; -; Genomic_DNA.
DR RefSeq; WP_008625157.1; NZ_LR215980.1.
DR AlphaFoldDB; F3QR57; -.
DR STRING; 762982.HMPREF9442_00656; -.
DR eggNOG; COG0317; Bacteria.
DR HOGENOM; CLU_012300_3_2_10; -.
DR OrthoDB; 9805041at2; -.
DR Proteomes; UP000005546; Unassembled WGS sequence.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR004811; RelA/Spo_fam.
DR InterPro; IPR045600; RelA/SpoT_AH_RIS.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR NCBIfam; TIGR00691; spoT_relA; 1.
DR PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR Pfam; PF13291; ACT_4; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF19296; RelA_AH_RIS; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS51880; TGS; 1.
PE 3: Inferred from homology;
FT DOMAIN 402..463
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
FT DOMAIN 665..737
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 737 AA; 84373 MW; 73DD9FB66345A983 CRC64;
MEQNAFFSAQ EKVRLAQLYR ELLKLSGNIL YPDDCKKLKT YLLEAVRRNL IQRNVFGMNP
ILNDMETALI VASEIGLTRG AILGIMVHTC VRCGYCTTED VEREFGVDVA GIIKGLNRIL
ELYDKNPSVE SENFRSLLLS FAEDMRVVLI MIANRVNIMR KIKDTENKEA QRKVSEEAAY
LYAPLAHKLG LYRLKSELED LSLKYLEHDA YYLIKEKLNA TKKSRDEYIE KFIRPIDEKL
KKAGLRFHMK GRTKSIHSIW QKMKKQHCGV EGIYDLFAIR IILDSALEKE KMECWQVYSI
ITDMYQPNPK RLRDWLSIPK SNGYESLHIT VLGPENKWVE VQIRTERMDE IAERGLAAHW
RYKGIKSGES GVDEWLNNIR SALENNDDLQ LMDQFKMDLY EDEVFVFTPK GDLFKFPKGA
TVLDFAYAIH TNVGDHCIGA KINEKNAPLR QKLNSGDQVE ILTANNQSPK QDWLNFVVTG
KARAKIRQAL KEMQAKQGAF AKELLERKFK NRKIEYDEPT MMHVIKKLGF KVVTDFYKSL
ANETTDINEV LDLYTEQQKI EAGLAEHTPA PSAESYNIPS EAELKAKTND DVLVIDQNLK
GLDFSLAKCC QPIYGDDVFG FVTVNGGIKI HRQDCPNAQE LRKRFGYRIV KARWAGKRGS
QYPITLKVIG NDDLGIVNNI TSIISKEEKI SLRSISIDSH DGLFSGTLTV MLDDTSKLQL
LEKKLKTIKG VKQVSRN
//
