ID F3SJD8_STRSA Unreviewed; 618 AA.
AC F3SJD8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Propanediol dehydratase, large subunit {ECO:0000313|EMBL:EGG39841.1};
DE EC=4.2.1.28 {ECO:0000313|EMBL:EGG39841.1};
GN Name=pduC {ECO:0000313|EMBL:EGG39841.1};
GN ORFNames=HMPREF9397_1260 {ECO:0000313|EMBL:EGG39841.1};
OS Streptococcus sanguinis SK1087.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888824 {ECO:0000313|EMBL:EGG39841.1, ECO:0000313|Proteomes:UP000003378};
RN [1] {ECO:0000313|EMBL:EGG39841.1, ECO:0000313|Proteomes:UP000003378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK1087 {ECO:0000313|EMBL:EGG39841.1,
RC ECO:0000313|Proteomes:UP000003378};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG39841.1}.
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DR EMBL; AFDP01000015; EGG39841.1; -; Genomic_DNA.
DR RefSeq; WP_002919537.1; NZ_GL883609.1.
DR AlphaFoldDB; F3SJD8; -.
DR PATRIC; fig|888824.3.peg.1239; -.
DR HOGENOM; CLU_449540_0_0_9; -.
DR Proteomes; UP000003378; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050215; F:propanediol dehydratase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 3.90.470.30; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.50.30.70; Swiveling domain of dehydratase reactivase alpha subunit; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR030994; DDR_dom.
DR InterPro; IPR040916; DDR_swiveling.
DR InterPro; IPR009191; DDRA.
DR InterPro; IPR028975; DDRA_swiveling_dom_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04491; reactive_PduG; 1.
DR Pfam; PF08841; DDR; 1.
DR Pfam; PF18427; DDR_swiveling; 1.
DR PIRSF; PIRSF011502; DdrA_PduG; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF82317; Swiveling domain of dehydratase reactivase alpha subunit; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR011502-2};
KW Lyase {ECO:0000313|EMBL:EGG39841.1};
KW Magnesium {ECO:0000256|PIRSR:PIRSR011502-1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR011502-1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR011502-2}.
FT DOMAIN 93..254
FT /note="DD-reactivating factor swiveling"
FT /evidence="ECO:0000259|Pfam:PF18427"
FT DOMAIN 275..604
FT /note="Diol dehydratase reactivase ATPase-like"
FT /evidence="ECO:0000259|Pfam:PF08841"
FT BINDING 11..13
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
FT BINDING 105
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-1"
FT BINDING 166
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-1"
FT BINDING 183
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-1"
FT BINDING 459..462
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
FT BINDING 559..560
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
FT BINDING 593
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR011502-2"
SQ SEQUENCE 618 AA; 66157 MW; 0C70A4D6F9D4474A CRC64;
MKRIIGVDIG NSSTESALAE VQDDGSIHFL ASAIADTTGI KGTKENVHGI YQSLRKLMEQ
TSFELGQVDL IRINEATPVI GDVAMETITE TVITESTMIG HNPRTPGGLG LGIGLTVDIL
DLVHHPIDGK YIVVVPKIID FDLVAQLINA YLAKGYQITA AILQADDGVL VNNRISQKIP
IVDEILFIDK VPLGMQAAVE VVEQGKVISQ LSNPYGIATV FGLSAEETKS IVPIARALIG
NRSAVVIKTP AGDIQARTIP AGSIQIIGKE HTLKVDISKG ADEIMEKIVY AGEISNVVGE
AGTNVGGMLE KVRQTMADLT EKEPSDIYIR DLLAVNTFAP ISVRGGVAGE FSMEQAVGIA
SMVNSDKLQM SIIAQEVERE LGITVEIGGA EAESAILGAL TTPGTDRPLA ILDLGAGSTD
ASIIDSRGQI LAVHLAGAGD MVTMLINSEL GLENHHLAED IKRYPLAKVE SLFHIRHEDG
TVQFFDKPLS GDLFARVVIV KENDEFVPID DGDYSIEKIK LVRQSAKERV FVTNAVRALK
RVSPTQNIRD IPFVVIVGGS ALDFEIPQLV TEALSQNAIV AGRGNVRGLV GPRNAVATGL
ILTYVREKWG DDYGISLY
//
