ID F3UXA2_STRSA Unreviewed; 842 AA.
AC F3UXA2;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Internalin protein {ECO:0000313|EMBL:EGJ39942.1};
GN Name=inlA {ECO:0000313|EMBL:EGJ39942.1};
GN ORFNames=HMPREF9380_1140 {ECO:0000313|EMBL:EGJ39942.1};
OS Streptococcus sanguinis SK49.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888808 {ECO:0000313|EMBL:EGJ39942.1, ECO:0000313|Proteomes:UP000006459};
RN [1] {ECO:0000313|EMBL:EGJ39942.1, ECO:0000313|Proteomes:UP000006459}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK49 {ECO:0000313|EMBL:EGJ39942.1,
RC ECO:0000313|Proteomes:UP000006459};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGJ39942.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFFO01000008; EGJ39942.1; -; Genomic_DNA.
DR RefSeq; WP_002933472.1; NZ_GL890985.1.
DR AlphaFoldDB; F3UXA2; -.
DR PATRIC; fig|888808.3.peg.1113; -.
DR eggNOG; COG4886; Bacteria.
DR HOGENOM; CLU_015932_0_0_9; -.
DR Proteomes; UP000006459; Unassembled WGS sequence.
DR Gene3D; 3.10.50.90; -; 3.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR023832; His_triad_protein.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR037228; PhtA_dom_sf.
DR InterPro; IPR006270; Strep_his_triad_rpt.
DR NCBIfam; TIGR01363; strep_his_triad; 1.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF04270; Strep_his_triad; 4.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF142887; PhtA domain-like; 3.
DR PROSITE; PS51450; LRR; 5.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..842
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039689451"
FT REGION 27..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..758
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..799
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 809..842
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 92469 MW; 1C80AEE59A9101D8 CRC64;
MKHNQKLLGL AGIILACNLC LAACQSQTSQ QKSSQEKVKT KQEVKKKSKA TKKEQVPGVD
KPTDDGFLFK SESQIKARTS EGLILEHDGH THFIFYSDLK NSKWAYLIPK DGQVPTGSTQ
LANQMSAADD GYVFNPRDIV SEDQYGYVVR HGNHFHYILK QSVGNLAQAP SYRPTPSSNP
TGHIYQPTLR PSVTQQQGAT KRQFAGIDYP TSDGFLFRGT GVTGKLASGL LADHNGHTHF
IPYEQLIASP WESLIPAEHK KAAEDAYYGR QGQAQPSPAP APAPEPTPSP SDKEEEVAKK
KAYLAQQLGI DESLIQVSDT DKGKVFIYPH GDHSHSTLVS EIDTTKPFDP HGNPHAHDAV
GMATLKTLGF DDEIIEDILH ATADSPFPSD ETDTEKMKAW LATVKYLNIG QRKDPLERKG
LELMPNIEVL GIGFTPIKDI RPVLQFKHLK QLWMTKTGVT NYDFLKEIPT LEGLDISQNG
ITDLSFLKNY PNLKTVAAAG NDLTDISPLA KLKNLESLNL DYNNISDISA LTKLSKLKAV
SLEHNQIQDV SALSQKEDLT RLFLSNNPNL NLNTLKASKL EELTADNSNV ESLNFLKNNP
NLTTLSLNEN RLTSLAGVEA AKNLVTLSAS QNKITSLDIP AAQSSLKNLN LAENELKNLE
GINQFRALDN LAVNKNKITT LALQEPNKTV TYINVSDNLI PKAELELNEN KIPKALAQHF
PDVQGGNIDN NKPAEPKEEN KEAPKESEPN KADVQGKPKS DKPASAQASN QGASNDSEHA
AGSPEAELNN RDENLENSSK PSPEEVPTAE NPELKDEPAQ AEDKENPKNS KDKEKEEKEA
NH
//
