ID F3YTU9_DESAF Unreviewed; 723 AA.
AC F3YTU9;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=Desaf_0120 {ECO:0000313|EMBL:EGJ48480.1};
OS Desulfocurvibacter africanus subsp. africanus str. Walvis Bay.
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae; Desulfocurvibacter.
OX NCBI_TaxID=690850 {ECO:0000313|EMBL:EGJ48480.1, ECO:0000313|Proteomes:UP000007844};
RN [1] {ECO:0000313|EMBL:EGJ48480.1, ECO:0000313|Proteomes:UP000007844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Walvis Bay {ECO:0000313|EMBL:EGJ48480.1,
RC ECO:0000313|Proteomes:UP000007844};
RX PubMed=21642452; DOI=10.1128/JB.05223-11;
RA Brown S.D., Wall J.D., Kucken A.M., Gilmour C.C., Podar M., Brandt C.C.,
RA Teshima H., Detter J.C., Han C.S., Land M.L., Lucas S., Han J.,
RA Pennacchio L., Nolan M., Pitluck S., Woyke T., Goodwin L., Palumbo A.V.,
RA Elias D.A.;
RT "Genome sequence of the mercury-methylating and pleomorphic Desulfovibrio
RT africanus Strain Walvis Bay.";
RL J. Bacteriol. 193:4037-4038(2011).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP003221; EGJ48480.1; -; Genomic_DNA.
DR RefSeq; WP_014258351.1; NC_016629.1.
DR AlphaFoldDB; F3YTU9; -.
DR STRING; 690850.Desaf_0120; -.
DR KEGG; daf:Desaf_0120; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_7; -.
DR Proteomes; UP000007844; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:EGJ48480.1};
KW Cilium {ECO:0000313|EMBL:EGJ48480.1};
KW Flagellum {ECO:0000313|EMBL:EGJ48480.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000007844};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 24..42
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 252..275
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 296..325
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT REGION 336..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 723 AA; 78488 MW; A97997DE46ED3A35 CRC64;
MASKAAKSST LSLNYERFAR QGDIMLAAGV VTILFVMLVP LPTLFIDLML TLSISLSLVV
LVTTMFMSSP LEFSIFPSLL LVTTLLRLSL NVATTRLILL HGDGGTEAAG NVIRAFGEFV
VGGNYFVGIV IFLILFFLNK MVITTGTTRI AEVAARFTLD AMPGKQMAIE ADLNAGLIDE
KEATLQRSNL RREADFYGAM DGAGKFVQGD VNAGLLITFV NIIGGILIGM IQKDMNWMEA
AQIYTLLTIG DGLVSTIPSL IISTSAGIIV SRAAAEAKMG EEFLAQLTFH PRALKLVSAI
LLVFAIVPGM PTVPFLVLSV LIFVVSKATQ VHRDSVDSLA PDRGKASGKL GSKSGAKALP
GGKAGEQPSS LDTPEEVQAL LPLDVLELEV GYGLIPLVDE EQNGNLLARI RSIRRQFALD
MGVIVPSLHL RDNLQLKPGQ YTVVIKGNEV ASAEILIDHL LAMDPGDVKH RIKGIETREP
AFNLPALWIP ERQKEEAMLA GYTVVDPSTV IATHLTEVFR HNLHEFLGRQ EIQSLLDHLA
KRAPKVVEEL VPDILPLGSV QKVLQNLVKE NVSIRDLLTI VEAMADFGSA VKDPDQLTEY
VRGRLSRTII KPYLGGDGTL SMITLHQSLE RVFQENLRQT DHGAYLSMDP MQAQRIIKAI
SKTHENAVAG DGQPVLLTSP SVRPHLAQLI TRFIPNLPVI SQAEIPSEIR LQTLAVVNVD
NAS
//
