ID F4B9I1_ACIHW Unreviewed; 449 AA.
AC F4B9I1;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Nucleotide excision repair helicase, Xpb2 {ECO:0000313|EMBL:AEE95127.1};
GN OrderedLocusNames=Ahos_2256 {ECO:0000313|EMBL:AEE95127.1};
OS Acidianus hospitalis (strain W1).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Acidianus.
OX NCBI_TaxID=933801 {ECO:0000313|EMBL:AEE95127.1, ECO:0000313|Proteomes:UP000008458};
RN [1] {ECO:0000313|EMBL:AEE95127.1, ECO:0000313|Proteomes:UP000008458}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W1 {ECO:0000313|EMBL:AEE95127.1,
RC ECO:0000313|Proteomes:UP000008458};
RX PubMed=21607549; DOI=10.1007/s00792-011-0379-y;
RA You X.Y., Liu C., Wang S.Y., Jiang C.Y., Shah S.A., Prangishvili D.,
RA She Q., Liu S.J., Garrett R.A.;
RT "Genomic analysis of Acidianus hospitalis W1 a host for studying
RT crenarchaeal virus and plasmid life cycles.";
RL Extremophiles 15:487-497(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=W1;
RA You X.Y., Liu C., Wang S.Y., Jiang C.Y., Shah S.A., Prangishvili D.,
RA Liu S.J., Garrett R.A.;
RT "Genomic analyses of Acidianus hospitalis W1 a host for studying
RT crenarchaeal virus and plasmid life cycles.";
RL Extremophiles 0:0-0(2011).
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DR EMBL; CP002535; AEE95127.1; -; Genomic_DNA.
DR RefSeq; WP_013777042.1; NC_015518.1.
DR AlphaFoldDB; F4B9I1; -.
DR STRING; 933801.Ahos_2256; -.
DR GeneID; 10601762; -.
DR KEGG; aho:Ahos_2256; -.
DR eggNOG; arCOG00874; Archaea.
DR HOGENOM; CLU_008213_6_0_2; -.
DR OrthoDB; 11644at2157; -.
DR Proteomes; UP000008458; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd17926; DEXHc_RE; 1.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.1170.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR040699; XPB_DRD.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18458; XPB_DRD; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:AEE95127.1};
KW Helicase {ECO:0000313|EMBL:AEE95127.1};
KW Hydrolase {ECO:0000313|EMBL:AEE95127.1};
KW Nucleotide-binding {ECO:0000313|EMBL:AEE95127.1}.
FT DOMAIN 78..222
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 315..449
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 449 AA; 51722 MW; 23B9E772E1D2D9CC CRC64;
MVRLSYYKGL LLSDYYAPGL KWSDEFKKYI GFAYKYRDVL EYFKREEIEI EDNVLDTLPF
PMIEDKITLR DYQAKALFFW NRAGRRGIIV LPTGAGKTAV GIKAITKVKT STLILVPTID
LLDQWYEKIK DSLNYSPGRI GGGYDELKAI TVITYDSAYT RVEEIGNKFA FVIFDEVHHL
PSEGYSQVAQ MLASPYRLGL TATPEREDSR HKLLPDLVGP VVFRLRTSDL AGKYLAEFEI
KKIYVSLTDE EKKKYEELRK KLKQFLSSRN MKLDSLESFH KLVKLAGRDP EAREALLAWH
TALRISVNSK AKIEKLRELL NEYCNEKENK IIIFTRDVEM AYNVSREFLI PVVTYKTSKD
ERSEILRKFK EGKYKVIVAS SVFDEGVDIP DANIGIVLGG YGTSRQMLQR LGRILRKKEG
EKNKALLIEI VTKGTSDYNL SKRRHRATV
//
