ID F4GD41_ALIDK Unreviewed; 1054 AA.
AC F4GD41;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(S) {ECO:0000313|EMBL:AEB84800.1};
GN OrderedLocusNames=Alide2_2441 {ECO:0000313|EMBL:AEB84800.1};
OS Alicycliphilus denitrificans (strain DSM 14773 / CIP 107495 / K601).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Alicycliphilus.
OX NCBI_TaxID=596154 {ECO:0000313|EMBL:AEB84800.1, ECO:0000313|Proteomes:UP000007938};
RN [1] {ECO:0000313|EMBL:AEB84800.1, ECO:0000313|Proteomes:UP000007938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14773 / CIP 107495 / K601
RC {ECO:0000313|Proteomes:UP000007938};
RX PubMed=21742888; DOI=10.1128/JB.00365-11;
RA Oosterkamp M.J., Veuskens T., Plugge C.M., Langenhoff A.A., Gerritse J.,
RA van Berkel W.J., Pieper D.H., Junca H., Goodwin L.A., Daligault H.E.,
RA Bruce D.C., Detter J.C., Tapia R., Han C.S., Land M.L., Hauser L.J.,
RA Smidt H., Stams A.J.;
RT "Genome Sequences of Alicycliphilus denitrificans Strains BC and K601T.";
RL J. Bacteriol. 193:5028-5029(2011).
RN [2] {ECO:0000313|EMBL:AEB84800.1, ECO:0000313|Proteomes:UP000007938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14773 / CIP 107495 / K601
RC {ECO:0000313|Proteomes:UP000007938};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Zeytun A., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Oosterkamp M.,
RA Pieper D., van Berkel W., Langenhoff A., Smidt H., Stams A., Woyke T.;
RT "Complete sequence of chromosome of Alicycliphilus denitrificans K601.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002657; AEB84800.1; -; Genomic_DNA.
DR AlphaFoldDB; F4GD41; -.
DR STRING; 596154.Alide2_2441; -.
DR KEGG; adk:Alide2_2441; -.
DR eggNOG; COG3614; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_59_4; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000007938; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007938};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 78..302
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 360..431
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 435..486
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 646..785
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 794..1047
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1054 AA; 116863 MW; 68BCD37B7C721CAA CRC64;
MSFFTAVRFS PRLWLPGMAV ALAGCVASYA LWRQQQTSMD AIAHLRFEQE TRLFAGALQR
RMESHTDLLQ GMRGLLTVDP QLRRAEFERV ASELALERSH PGVKNINFTR YVPGAQRTAF
EAQARGDAHM DGSLPRDFAI HPEQERPEYF VVDFLWPREG NADVQGLEIH SQPDNLEAMM
RTRAGGELVA SAPFDLHQET ERRTGIIIRI PVFAHGTPPG QREAARFLGA VGVSIRIDDV
IQMLRAEGYL KGLTLVMSDI GPSGAETGSA ALLFDSTSKP AQAADMERVQ EVQVGGRRWR
LQFQSAGTFL SAQEARLPGL LGLGGMLITA LLTAMVSMLV LRRVRALGDV QQAGVALRES
EERFRAVFSQ AAVGMAQVDL HSDRMVRVNR KLCDLLGYTE AELQQLRFQD ISDPRDLDAD
LAFMERMRSG KISEFRMEKR YCRKDGEIVW AELMVSRLCL EGRPESHLAV VQDIGERKQM
EQALSDSEQH LLGILNHMPV GVNLVRGRAI AFRNDRHVQI CGYGEQEAPD VDSWWRLVMP
DAAERHQARE AWKAACMAAR HAADGAIRPV ECHITSKAGL LRTVEISGVM LEDSHIVTMV
DQSQRRQAEE EVRYLAYNDP LTGLPNRRLL LDRLQQALAM SARHQLCGAV LMLDLDNFKH
INETQGHDMG DRLLHAVALR LRACIPEDDT LARHGGDEFV VVLKDLGASP QEAATRAEAM
GLQILDAMRE PFALGGGEPR HTTLSVGIVI FQGLHESADE LLKRSDMAMY EAKAAGRDAL
RFFDPQVQAQ MTARVALEAD MRSGLEAGEF ELFYQPKMVH GRITGAEALL RWKHPVKGYI
PPSEFIPLAE QSGLILRMGQ WVLRTACERL ALWSSHPVLG QLSVAVNVSP RQFHEAGFVP
EVLEALAGTG ADARRLRLEL TEGLLLQDVE DTVAKMVQLR GYGVGFSLDD FGTGYSSLAY
LKRLPLHELK IDQSFVRDVL TDPNDAAIAR TIVALGTSLG LQVVAEGVET EAQRVFLERS
GCHAWQGYLL SRPLPGLAFE DLVLEHAASA GATA
//
