ID F4GF45_ALIDK Unreviewed; 486 AA.
AC F4GF45;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:AEB86149.1};
GN OrderedLocusNames=Alide2_3824 {ECO:0000313|EMBL:AEB86149.1};
OS Alicycliphilus denitrificans (strain DSM 14773 / CIP 107495 / K601).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Alicycliphilus.
OX NCBI_TaxID=596154 {ECO:0000313|EMBL:AEB86149.1, ECO:0000313|Proteomes:UP000007938};
RN [1] {ECO:0000313|EMBL:AEB86149.1, ECO:0000313|Proteomes:UP000007938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14773 / CIP 107495 / K601
RC {ECO:0000313|Proteomes:UP000007938};
RX PubMed=21742888; DOI=10.1128/JB.00365-11;
RA Oosterkamp M.J., Veuskens T., Plugge C.M., Langenhoff A.A., Gerritse J.,
RA van Berkel W.J., Pieper D.H., Junca H., Goodwin L.A., Daligault H.E.,
RA Bruce D.C., Detter J.C., Tapia R., Han C.S., Land M.L., Hauser L.J.,
RA Smidt H., Stams A.J.;
RT "Genome Sequences of Alicycliphilus denitrificans Strains BC and K601T.";
RL J. Bacteriol. 193:5028-5029(2011).
RN [2] {ECO:0000313|EMBL:AEB86149.1, ECO:0000313|Proteomes:UP000007938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14773 / CIP 107495 / K601
RC {ECO:0000313|Proteomes:UP000007938};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Zeytun A., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Oosterkamp M.,
RA Pieper D., van Berkel W., Langenhoff A., Smidt H., Stams A., Woyke T.;
RT "Complete sequence of chromosome of Alicycliphilus denitrificans K601.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP002657; AEB86149.1; -; Genomic_DNA.
DR RefSeq; WP_013722912.1; NC_015422.1.
DR AlphaFoldDB; F4GF45; -.
DR STRING; 596154.Alide2_3824; -.
DR KEGG; adk:Alide2_3824; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_1_0_4; -.
DR OrthoDB; 9803213at2; -.
DR Proteomes; UP000007938; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000007938}.
FT DOMAIN 44..107
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 135..243
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 251..484
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 486 AA; 51514 MW; 6DC8A4DF4922EE85 CRC64;
MISREPTIER LAVARELLLA PFGLDESHLY RALAEIRAHQ VDDADLYFQY TRSEGWSLEE
GIVKTGSFSI DQGVGVRAVS GEKTAFAYSD DISEASLLDA ARTVRSISAT AQSGRARVAS
KKIAKSRSLY PHIDPIASMD STAKVQLLER AEQRARAKDP RVAQVMAGLA SEYDVVLVAR
ADGTLAADVR PLVRMSVTVI AEQGGRREVG SSGGGGRFGL AYFSDEQIAQ YVDEAVNAAL
VNLESRPAPA GEMTVVLGPG WPGVLLHEAV GHGLEGDFNR KGSSAFSGRI GQRVAAKGVT
VLDDGTLADR RGSLNVDDEG HATQRNVLIE DGILKGYIQD AMNARLMKVA PTGNGRRESY
AHIPMPRMTN TYMLGGDKDP QEIVASIKRG LYATNFGGGQ VDITSGKFVF SASEAYWVEG
GKILYPVKGA TIVGSGPESL KKVSMIGNDM ALDSGVGTCG KEGQSVPVGV GQPTLRIDGI
TVGGTA
//
