ID   F4HJQ7_PYRSN            Unreviewed;      1029 AA.
AC   F4HJQ7;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=ATP-dependent RNA helicase HepA, putative {ECO:0000313|EMBL:AEC52475.1};
GN   OrderedLocusNames=PNA2_1560 {ECO:0000313|EMBL:AEC52475.1};
OS   Pyrococcus sp. (strain NA2).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=342949 {ECO:0000313|EMBL:AEC52475.1, ECO:0000313|Proteomes:UP000008293};
RN   [1] {ECO:0000313|EMBL:AEC52475.1, ECO:0000313|Proteomes:UP000008293}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA2 {ECO:0000313|EMBL:AEC52475.1,
RC   ECO:0000313|Proteomes:UP000008293};
RX   PubMed=21602357; DOI=10.1128/JB.05150-11;
RA   Lee H.S., Bae S.S., Kim M.S., Kwon K.K., Kang S.G., Lee J.H.;
RT   "Complete genome sequence of hyperthermophilic Pyrococcus sp. strain NA2,
RT   isolated from a deep-sea hydrothermal vent area.";
RL   J. Bacteriol. 193:3666-3667(2011).
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DR   EMBL; CP002670; AEC52475.1; -; Genomic_DNA.
DR   RefSeq; WP_013749025.1; NC_015474.1.
DR   AlphaFoldDB; F4HJQ7; -.
DR   STRING; 342949.PNA2_1560; -.
DR   GeneID; 10555046; -.
DR   KEGG; pyn:PNA2_1560; -.
DR   PATRIC; fig|342949.8.peg.1565; -.
DR   eggNOG; arCOG00871; Archaea.
DR   HOGENOM; CLU_009519_0_0_2; -.
DR   OrthoDB; 6396at2157; -.
DR   Proteomes; UP000008293; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd18793; SF2_C_SNF; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024975; NOV_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR049730; SNF2/RAD54-like_C.
DR   PANTHER; PTHR10799:SF971; RNA POLYMERASE-ASSOCIATED PROTEIN RAPA; 1.
DR   PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF13020; NOV_C; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000313|EMBL:AEC52475.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          48..208
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          391..544
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   COILED          301..351
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          575..605
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1029 AA;  119865 MW;  D587322B25D96E62 CRC64;
     MIDYVRFRVG VDSNFIFTRY LYDPVTVLAT SKIDLLPYQI EDFLTLLDMA ETGEVRVLLA
     YETGLGKTIV TGLFLKEMLL RDENQRVLIL VPPNIRRQWK RELKEKFNLD FKVDFELDKS
     PDMLKEKWLI ASMDTLKLEH WKKWIEEYEY RWDIVVVDEL HRAKEGNQRA QLIQLVSSRT
     KHFIALTATP HDGKEENFIF RLSLINPSVD ESNYKDFVRQ YVIRRIKREV TDLDGRKLFP
     QLPITRTVEI EPTPEEREFY RAVEEYIRHY YRLASQENNR AIGLVATVIG RTVSSSIRAG
     VAALKRRLNR LTMEAAGIAT ETSQIDPDEV LRKLQEAMEE ADDKTVEQLR EEIINFIPPQ
     LRDELKVEEE RLKKLIEMGE SIIRRERIDT KAKELLKIVD EHLEKGNKVI IFTEYLDTLF
     YLNEILGEKY GPERVTLIYG SMKPEEKDES VRKLWAEDGA SILIATDAAG ESLDLQAANV
     VINYEIPWNP VVYIQRIGRV YRYGQKKPVI FIYGILPVFK VERRVLEVVL DKINKIKTDF
     DLGSAEIVGE IISQKDIEKV IMETYANLLN TEEAREKISR NFEEKRRLLN KIKEALSKAK
     AVQKHVRLER LLKDKNVLEL VTEQHVIRYL QYLRETGLVY GSIGDQFGHM WINDKEPNFD
     NIKLVNKKQV KAIWKRVQKA SEIVRPNLDD LGAMKAILLG LESEGVAAFL WEGETLYGEV
     RIATFTDGLG TVVNEIPVVV LENGDVKPVT WLKELEVLDE IDHDKIKELL QKQVDTKVAI
     NSELIKCLRR DVHESVKNRA TLLIGKYHSE IRKVSSDTKL DKYIRERKLK ELREKVKQEM
     NRKRAVEVSF SEKPIGKVLL IGVNDANKFT LKKSSGESKP FDPELWKRKK EVELAAMAVV
     EWWEKHKFGR NPRDVSADGR GYDIESVGEN HETFYVEVKG FKREPVKVEL TENEYHAASY
     YKDKYLLYIV PHAIENYQRI LQGLEPEEPI IIPDPVNTLK DLIEIEWKPR YIINLKGLSL
     NQERVQGDT
//