ID F4HS76_ARATH Unreviewed; 482 AA.
AC F4HS76;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN Name=NHO1 {ECO:0000313|EMBL:AEE36408.1, ECO:0000313|TAIR:AT1G80460};
GN Synonyms=GLI1 {ECO:0000313|EMBL:AEE36408.1};
GN OrderedLocusNames=At1g80460 {ECO:0000313|Araport:AT1G80460,
GN ECO:0000313|EMBL:AEE36408.1};
GN ORFNames=T21F11.21 {ECO:0000313|EMBL:AEE36408.1}, T21F11_21
GN {ECO:0000313|EMBL:AEE36408.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE36408.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEE36408.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156}.
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DR EMBL; CP002684; AEE36408.1; -; Genomic_DNA.
DR RefSeq; NP_001031307.1; NM_001036230.1.
DR AlphaFoldDB; F4HS76; -.
DR SMR; F4HS76; -.
DR ProteomicsDB; 206112; -.
DR EnsemblPlants; AT1G80460.2; AT1G80460.2; AT1G80460.
DR GeneID; 844385; -.
DR Gramene; AT1G80460.2; AT1G80460.2; AT1G80460.
DR Araport; AT1G80460; -.
DR TAIR; AT1G80460; NHO1.
DR HOGENOM; CLU_009281_2_2_1; -.
DR PhylomeDB; F4HS76; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HS76; baseline and differential.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 2.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4HS76,
KW ECO:0007829|ProteomicsDB:F4HS76};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 8..262
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 272..412
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 482 AA; 52483 MW; C727FE079E8A12CB CRC64;
MAKENGFIGS IDQGTTSTRF IIYDHDARPV ASHQVEFTQF YPEAGWVEHD PMEILESVKV
CIAKALDKAT ADGHNVDGGL KAIGLTDQRE TTVVWSKSTG LPLHKAIVWM DARTSSICRR
LEKELSGGRS HFVESCGLPI STYFSAMKLL WLMENVDDVK DAIKKGDAIF GTIDTWLIWN
MTGGINGGLH VTDVTNASRT MLMNLKTLSW DQDTLKTLGI PAEILPKIVS NSEVIGEICK
GWPIPGIKIA GCLGDQHAAM LGQACRKGEA KSTYGTGAFI LLNTGEVPIK SGHGLLTTLA
YKLGPQAQTN YALEGSIAIA GAAVQWLRDS LGIIKSASEI EDLAAMVDST GGVYFVPAFN
GLFAPWWRED ARGVCIGITR FTNKSHIARA VLESMCFQVK DVLDSMNKDA GEKGSLNNGK
GEFLLRVDAV GFWKEADIFE SGEKAKNSKV FRPAMEEGIR KKKVASWCKA VERTFDLADL
SI
//
