ID F4I818_ARATH Unreviewed; 637 AA.
AC F4I818;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Vesicle-associated protein 1-4 {ECO:0000313|EMBL:AEE32645.1};
GN OrderedLocusNames=At1g51270 {ECO:0000313|Araport:AT1G51270,
GN ECO:0000313|EMBL:AEE32645.1};
GN ORFNames=F11M15.13 {ECO:0000313|EMBL:AEE32645.1}, F11M15_13
GN {ECO:0000313|EMBL:AEE32645.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE32645.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEE32645.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SIMILARITY: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17)
CC family. {ECO:0000256|ARBA:ARBA00008932}.
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DR EMBL; CP002684; AEE32645.1; -; Genomic_DNA.
DR RefSeq; NP_001154418.1; NM_001160946.2.
DR AlphaFoldDB; F4I818; -.
DR SMR; F4I818; -.
DR ProteomicsDB; 210104; -.
DR EnsemblPlants; AT1G51270.3; AT1G51270.3; AT1G51270.
DR GeneID; 841550; -.
DR Gramene; AT1G51270.3; AT1G51270.3; AT1G51270.
DR Araport; AT1G51270; -.
DR TAIR; AT1G51270; -.
DR HOGENOM; CLU_034592_0_0_1; -.
DR OrthoDB; 5623321at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I818; baseline and differential.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR016763; VAP.
DR PANTHER; PTHR10809:SF6; AT11025P-RELATED; 1.
DR PANTHER; PTHR10809; VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN; 1.
DR Pfam; PF00635; Motile_Sperm; 2.
DR Pfam; PF01582; TIR; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF49354; PapD-like; 2.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50202; MSP; 2.
DR PROSITE; PS50104; TIR; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4I818};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 1..126
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
FT DOMAIN 176..296
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
FT DOMAIN 356..493
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 132..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 71930 MW; DA12F686FC78ED38 CRC64;
MSTDELLTFD HVDIRFPIEL NKQGSCSLNL TNKTDNYVAF KAQTTKPKMY CVKPSVGVVL
PRSSCEVLVV MQALKEAPAD RQCKDKLLFQ CKVVEPGTMD KEVTSEMFSK EAGHRVEETI
FKIIYVAPPQ PQSPVQEGLE DGSSPSASVS DKGNASEVFV GPSVGIVDLI RMSDELLIID
PVDVQFPIEL NKKVSCSLNL TNKTENYVAF KAKTTNAKKY YVRPNVGVVL PRSSCEVLVI
MQALKEAPAD MQCRDKLLFQ CKVVEPETTA KDVTSEMFSK EAGHPAEETR LKVMYVTPPQ
PPSPVQEGTE EGSSPRASVS DNGNASEAFV DMLRSLLVPL FSNAASSTDD HGITLPQYQV
FINFRGDELR NSFVGFLVKA MRLEKINVFT DEVELRGTNL NYLFRRIEES RVAVAIFSER
YTESCWCLDE LVKMKEQMEQ GKLVVVPVFY RLNATACKRF MGAFGDNLRN LEWEYRSEPE
RIQKWKEALS SVFSNIGLTS DIRSNESKFV DSIVEEVKKV LIKIADNFFK DHLPWKFPRL
TLTDGTTIYI KRSYFVGFLV QETANVSLDD HDLRDSPLVT NYVCFTTPIN DLLKFHTLLI
SLSHKVSSKV HHSSLFFATM YLFEFESFTF IVWLSPT
//
