ID F4KDN1_ARATH Unreviewed; 824 AA.
AC F4KDN1;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=RNA-binding KH domain-containing protein {ECO:0000313|EMBL:AED97883.1};
GN Name=HEN4 {ECO:0000313|EMBL:AED97883.1, ECO:0000313|TAIR:AT5G64390};
GN Synonyms=HUA ENHANCER 4 {ECO:0000313|EMBL:AED97883.1}, MSJ1.23
GN {ECO:0000313|EMBL:AED97883.1}, MSJ1_23 {ECO:0000313|EMBL:AED97883.1};
GN OrderedLocusNames=At5g64390 {ECO:0000313|Araport:AT5G64390,
GN ECO:0000313|EMBL:AED97883.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AED97883.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AED97883.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130714; DOI=10.1038/35048507;
RG Kazusa DNA Research Institute;
RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium;
RG European Union Arabidopsis Genome Sequencing Consortium;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., See L.H., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Dusterhoft A., Stiekema W., Pohl T., Entian K.D.,
RA Terryn N., Hartley N., Bent E., Johnson S., Langham S.A., McCullagh B.,
RA Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H.,
RA Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Lankhorst R.K., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S.,
RA Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J.,
RA Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.W., Bevan M., Fransz P.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
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DR EMBL; CP002688; AED97883.1; -; Genomic_DNA.
DR RefSeq; NP_974990.1; NM_203261.2.
DR AlphaFoldDB; F4KDN1; -.
DR SMR; F4KDN1; -.
DR ProteomicsDB; 218679; -.
DR EnsemblPlants; AT5G64390.2; AT5G64390.2; AT5G64390.
DR GeneID; 836560; -.
DR Gramene; AT5G64390.2; AT5G64390.2; AT5G64390.
DR Araport; AT5G64390; -.
DR TAIR; AT5G64390; HEN4.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4KDN1; baseline and differential.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22459; KH-I_PEPPER_rpt1_like; 2.
DR CDD; cd22460; KH-I_PEPPER_rpt2_like; 2.
DR Gene3D; 3.30.310.210; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF173; KH DOMAIN-CONTAINING PROTEIN HEN4-RELATED; 1.
DR Pfam; PF00013; KH_1; 4.
DR SMART; SM00322; KH; 4.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 4.
DR PROSITE; PS50084; KH_TYPE_1; 5.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4KDN1,
KW ECO:0007829|ProteomicsDB:F4KDN1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 45..115
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 148..222
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 450..523
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 540..615
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..688
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 824 AA; 90239 MW; 697B9FA07C78CB99 CRC64;
MERNSVKFHA EKRSGAFDPG SGFGSSKRVK THHTQLLSAL VVPVGHAAFR LLCPLSHVGA
VIGKSGNVIK QLQQSTGAKI RVEEPPSGSP DRVITIIAQA DSKSRVKLGA NNNGNAEGEK
KEEEVEVSKA QGALIKVFEL LAAEADSDTV VCRLLTESSH AGAVIGKGGQ MVGSIRKETG
CKISIRIENL PICADTDDEM VEVEGNAIAV KKALVSISRC LQNCQSIDKV RMVGNRPLEK
EFQASLHRPI ETIIQESLPR SVEVNPYDYR LRNDEIFPRG TVARANDVIP HDTLHLRRIE
AVPQGALRMH IEADRQDVLR RHVEADRQDA LRRRIDVVPQ ETLYMPSDVL RGDCFRQHRE
RDDSHDSLHR PFEMVPRDAM GMPFESFPRD AYGRPIETMT QETLRGQSAD YLAHRYSTLD
THPHSFTTSA SMANTATMKP PPSEVEVGNQ DVVFKILCST ENAGGVIGTG GKVVRMLHSE
TGAFINVGNT LDDCEERLIA VTASENPECQ SSPAQKAIML IFSRLFELAT NKILDNGPRS
SITARLVVPT SQIGCVLGKG GVIVSEMRKT TGAAIQILKV EQNPKCISEN DQVVQITGEF
PNVREAIFHI TSRLRDSVFS NSMKNSLAKS SSALTTERFY DRQSDNPLSI GSHQSVSNPA
TNSSSLHRRS EDSFLSGSHS SVNYSRSVGT DPYIRPEDPF PDRFNPSAGY SHNFGRRFTM
DHSDNSHHLT EAPSRLWASP PPAAPRGLSD ASGGLSSARA GHVLGSGHKS AIVTNTTVEI
RVPANAMSFV YGEQGYNLEQ LRQVSHFLFT NLLLVFPIAS SKRG
//
