ID F4MR09_MYCML Unreviewed; 122 AA.
AC F4MR09;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=Large ribosomal subunit protein bL12 {ECO:0000256|HAMAP-Rule:MF_00368};
GN Name=L7 {ECO:0000313|EMBL:CBW54543.1};
GN Synonyms=rplL {ECO:0000256|HAMAP-Rule:MF_00368};
GN ORFNames=MLC_8130 {ECO:0000313|EMBL:CBW54543.1};
OS Mycoplasma mycoides subsp. capri LC str. 95010.
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=862259 {ECO:0000313|EMBL:CBW54543.1, ECO:0000313|Proteomes:UP000010103};
RN [1] {ECO:0000313|EMBL:CBW54543.1, ECO:0000313|Proteomes:UP000010103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=95010 {ECO:0000313|EMBL:CBW54543.1,
RC ECO:0000313|Proteomes:UP000010103};
RA Thiaucourt F., Manso-Silvan L., Salah W., Barbe V., Berger A., Jacob D.,
RA Breton M., Dupuy V., Lomenech A.M., Blanchard A., Sirand-Pugnet P.;
RT "Mycoplasma mycoides, from "mycoides Small Colony" to "capri". A
RT microevolutionary perspective.";
RL BMC Genomics 0:0-0(2011).
RN [2] {ECO:0000313|Proteomes:UP000010103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=95010 {ECO:0000313|Proteomes:UP000010103};
RX PubMed=21324191; DOI=10.1186/1471-2164-12-114;
RA Thiaucourt F., Manso-Silvan L., Salah W., Barbe V., Berger A., Jacob D.,
RA Breton M., Dupuy V., Lomenech A.M., Blanchard A., Sirand-Pugnet P.;
RT "Mycoplasma mycoides, from "mycoides Small Colony" to "capri". A
RT microevolutionary perspective.";
RL BMC Genomics 12:114-114(2011).
RN [3] {ECO:0000313|Proteomes:UP000010103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=95010 {ECO:0000313|Proteomes:UP000010103};
RA Thiaucourt F., Manso-Silvan L., Salah W., Barbe V., Berger A., Jacob D.,
RA Breton M., Dupuy V., Lomenech A.M., Blanchard A., Sirand-Pugnet P.;
RT "Mycoplasma mycoides, from mycoides Small Colony to capri. A
RT microevolutionary perspective.";
RL BMC Genomics 12:0-0(2011).
CC -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC interact with GTP-bound translation factors. Is thus essential for
CC accurate translation. {ECO:0000256|HAMAP-Rule:MF_00368}.
CC -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC fashion. Binds GTP-bound translation factors. {ECO:0000256|HAMAP-
CC Rule:MF_00368}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC {ECO:0000256|ARBA:ARBA00007197, ECO:0000256|HAMAP-Rule:MF_00368}.
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DR EMBL; FQ377874; CBW54543.1; -; Genomic_DNA.
DR RefSeq; WP_013729911.1; NC_015431.1.
DR AlphaFoldDB; F4MR09; -.
DR KEGG; mml:MLC_8130; -.
DR HOGENOM; CLU_086499_3_2_14; -.
DR OrthoDB; 9811748at2; -.
DR Proteomes; UP000010103; Chromosome.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1390.10; -; 1.
DR Gene3D; 1.20.5.710; Single helix bin; 1.
DR HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR InterPro; IPR000206; Ribosomal_bL12.
DR InterPro; IPR013823; Ribosomal_bL12_C.
DR InterPro; IPR014719; Ribosomal_bL12_C/ClpS-like.
DR InterPro; IPR008932; Ribosomal_bL12_oligo.
DR InterPro; IPR036235; Ribosomal_bL12_oligo_N_sf.
DR NCBIfam; TIGR00855; L12; 1.
DR PANTHER; PTHR45987; 39S RIBOSOMAL PROTEIN L12; 1.
DR PANTHER; PTHR45987:SF4; 39S RIBOSOMAL PROTEIN L12, MITOCHONDRIAL; 1.
DR Pfam; PF00542; Ribosomal_L12; 1.
DR Pfam; PF16320; Ribosomal_L12_N; 1.
DR SUPFAM; SSF54736; ClpS-like; 1.
DR SUPFAM; SSF48300; Ribosomal protein L7/12, oligomerisation (N-terminal) domain; 1.
PE 3: Inferred from homology;
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW Rule:MF_00368};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW Rule:MF_00368}.
FT DOMAIN 4..47
FT /note="Large ribosomal subunit protein bL12
FT oligomerization"
FT /evidence="ECO:0000259|Pfam:PF16320"
FT DOMAIN 56..122
FT /note="Large ribosomal subunit protein bL12 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00542"
SQ SEQUENCE 122 AA; 12906 MW; 01A20743B0842284 CRC64;
MPITKDEIIK ALEEMKLNEL NELVKAIEDH FGVVASVGVA AAAPTEATNA APTEVSVVMT
SVGQQKVAVI KVVKELTGVG LMDAKKIVDG TMPVTIKEHV KPEEAEEMKA KLVEAGASID
LK
//
