ID F4S1V2_MELLP Unreviewed; 604 AA.
AC F4S1V2;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN ORFNames=MELLADRAFT_79033 {ECO:0000313|EMBL:EGG01443.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family.
CC {ECO:0000256|ARBA:ARBA00009580}.
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DR EMBL; GL883138; EGG01443.1; -; Genomic_DNA.
DR RefSeq; XP_007415293.1; XM_007415231.1.
DR AlphaFoldDB; F4S1V2; -.
DR STRING; 747676.F4S1V2; -.
DR EnsemblFungi; EGG01443; EGG01443; MELLADRAFT_79033.
DR GeneID; 18933205; -.
DR KEGG; mlr:MELLADRAFT_79033; -.
DR VEuPathDB; FungiDB:MELLADRAFT_79033; -.
DR eggNOG; ENOG502RZZ0; Eukaryota.
DR HOGENOM; CLU_452027_0_0_1; -.
DR InParanoid; F4S1V2; -.
DR OrthoDB; 1424190at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR022778; CDKN3.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR23339:SF98; CYCLIN-DEPENDENT KINASE INHIBITOR 3-RELATED; 1.
DR PANTHER; PTHR23339; TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE; 1.
DR Pfam; PF05706; CDKN3; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001072}.
FT DOMAIN 482..589
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 96..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..127
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 604 AA; 66563 MW; 45DC8675B8707252 CRC64;
MDFNKNSTAI AQVMSPSATH PGHSLPSATS MSHTHIRSLA NQNVHQGSIS LELQRNYLND
CVKAVPSASP LVTPEMGERL CRMASQHYMS DYNRYKRGQH PNPLLSQQLP QPNYTTPGVT
SQHQQGYPRV VDRPAERLPA CPPFQHHVTV PAGVSSDQTQ ASNQPTQPLP KTSVVHDHQF
ASSNPSDLVE SNPEKNLKSS QMVFNPSATS TASNGYNHHP MPVDAVTNPA TMESKLANPT
EKRKFQDRTP SPAAEQLALD GGHTLIGVVS GDHVATKPDV VKTVHGSSVK TSQTHPMNIS
PVVPPELSVA LADFYLTSPI TNEQPLPSLP VDLYDLTGPH ASRAYEEFHI HHQQRLYHFS
QHHQPGLPVK DSPLGQSPPS INAVRLGNML LSSCPGKKVR MFDTLAQRQA AGNRSPICRD
LKSDLSRAQS IGVRAIICCL DDEELNYLGS PWPEYQAVAS ACGLAVIRIP MAEGFAPHKG
VDEIDRVIQI VLENWTMKGY DVLCHCRGGV GRAGLVACCW MLKIGLINKP IHDIEHDHPR
MDLANFNPAT KGQTPHPVPR NSVLVQVEKV IEVIRRRRSV KAIETPQQVH FIMEYADWLD
HQRK
//
