ID F4S9J8_MELLP Unreviewed; 548 AA.
AC F4S9J8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=SMAD/FHA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MELLADRAFT_95497 {ECO:0000313|EMBL:EGF98650.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
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DR EMBL; GL883171; EGF98650.1; -; Genomic_DNA.
DR RefSeq; XP_007418068.1; XM_007418006.1.
DR AlphaFoldDB; F4S9J8; -.
DR STRING; 747676.F4S9J8; -.
DR EnsemblFungi; EGF98650; EGF98650; MELLADRAFT_95497.
DR GeneID; 18937261; -.
DR KEGG; mlr:MELLADRAFT_95497; -.
DR VEuPathDB; FungiDB:MELLADRAFT_95497; -.
DR eggNOG; KOG3872; Eukaryota.
DR HOGENOM; CLU_017542_0_0_1; -.
DR InParanoid; F4S9J8; -.
DR OrthoDB; 463769at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:UniProt.
DR GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR15067; E3 UBIQUITIN-PROTEIN LIGASE RNF8; 1.
DR PANTHER; PTHR15067:SF8; E3 UBIQUITIN-PROTEIN LIGASE RNF8; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF17123; zf-RING_11; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001072};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 162..224
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 319..363
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 29..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 84..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 59943 MW; 5A552FBDE9FB8B51 CRC64;
MPRNRRSMSQ PPPIPSVIRS ATDRLRSNHH LSPTQSVTPQ SILSSSHPTP TPTVSHPLSG
DSNNNNLANS ILRNNQTVAD LSTTINTTDN TPTSSSEIPL SEPQVQTPSQ VQSPAQSTNQ
TAQSTNQQPQ TLYSLRLVPH LDATRSLHFE PIERKIASST SLKIGRFTDR SLPNNEINLN
DNRIAFKSKV VSRGHADIFT DQSGQFFIKD TKSSSGTFLN HIRLSAPGGE SKPFPLRDGD
VLQLGVDYQG GTEEIYRCVK MRVELNRGWQ RAANNFNQQA LAQLRALGGE SNISDSNSSA
NKANKDPSKP EPLKPVSDCC ICLFGVTVCQ ALFIAPCSHV YHFKCIRPLL QMHHPGFSCP
LCRTFADLEA DVETEDPPEP EVPKSNPNGT GLETQLGSPV VISDQIVIDD FNQSSQMDVQ
ATAVGMTNVS TPHDINAQNR DEDIVMEDNT LFPDRTLHTS PDLNGSSNPT NLSGSSLSRH
DTLHTPIIRS TTSNNHHPLS NSYQEGGSNG HTVIDRALTG PNGPGTLRNQ TQKKKEDEQM
ELLNEEPL
//
