ID   F4V4S5_ECOLX            Unreviewed;       306 AA.
AC   F4V4S5;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Putative transcriptional regulator, RpiR family {ECO:0000313|EMBL:EGI40675.1};
GN   ORFNames=ECNG_00592 {ECO:0000313|EMBL:EGI40675.1};
OS   Escherichia coli TA280.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=656444 {ECO:0000313|EMBL:EGI40675.1, ECO:0000313|Proteomes:UP000004877};
RN   [1] {ECO:0000313|EMBL:EGI40675.1, ECO:0000313|Proteomes:UP000004877}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TA280 {ECO:0000313|EMBL:EGI40675.1,
RC   ECO:0000313|Proteomes:UP000004877};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Feldgarden M., Gordon D.M., Johnson J.R., Johnston B.D., Young S., Zeng Q.,
RA   Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Escherichia coli TA280.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL884367; EGI40675.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4V4S5; -.
DR   SMR; F4V4S5; -.
DR   HOGENOM; CLU_055769_0_2_6; -.
DR   Proteomes; UP000004877; Unassembled WGS sequence.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05013; SIS_RpiR; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR000281; HTH_RpiR.
DR   InterPro; IPR047640; RpiR-like.
DR   InterPro; IPR035472; RpiR-like_SIS.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR30514; GLUCOKINASE; 1.
DR   PANTHER; PTHR30514:SF17; HTH-TYPE TRANSCRIPTIONAL REGULATOR MURR; 1.
DR   Pfam; PF01418; HTH_6; 1.
DR   Pfam; PF01380; SIS; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF53697; SIS domain; 1.
DR   PROSITE; PS51071; HTH_RPIR; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   4: Predicted;
FT   DOMAIN          25..101
FT                   /note="HTH rpiR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51071"
FT   DOMAIN          149..289
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
SQ   SEQUENCE   306 AA;  33638 MW;  75FE3F5EC282A750 CRC64;
     MEYKIHSRLS HIACCRHYFI ARKDMNGLLR IRQRYQGLAQ SDKKLADYLL LQPDTARHLS
     SQQLANEAGV SQSSVVKFAQ KLGYKGFPAL KLALSEALAS QPESPSVPIH NQIRGDDPLR
     LVGEKLIKEN TAAMYATLNV NSEEKLHECV AMLRSARRII LTGIGASGLV AQNFAWKLMK
     IGFNAAAVRD MHALLATVQA SSPDDLLLAI SYTGVRRELN LAADEMLRVG GKVLAITGFT
     PNALQQRASH CLYTIAEEQA TNSASISACH AQGMLTDLLF IALIQQDLEL APERIRHSEA
     LVKKLV
//