ID F4WDE9_ACREC Unreviewed; 1252 AA.
AC F4WDE9;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-3 {ECO:0000313|EMBL:EGI67729.1};
GN ORFNames=G5I_03602 {ECO:0000313|EMBL:EGI67729.1};
OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS echinatior).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Acromyrmex.
OX NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN [1] {ECO:0000313|EMBL:EGI67729.1}
RP NUCLEOTIDE SEQUENCE.
RA Nygaard S., Zhang G.;
RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT adaptations to social evolution and fungus farming.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL888087; EGI67729.1; -; Genomic_DNA.
DR AlphaFoldDB; F4WDE9; -.
DR STRING; 103372.F4WDE9; -.
DR eggNOG; KOG2353; Eukaryota.
DR InParanoid; F4WDE9; -.
DR Proteomes; UP000007755; Unassembled WGS sequence.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR CDD; cd01463; vWA_VGCC_like; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013680; VDCC_a2/dsu.
DR InterPro; IPR013608; VWA_N.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10166:SF31; CA[2+] CHANNEL MUSCLE-SPECIFIC ALPHA2_DELTA SUBUNIT, ISOFORM A; 1.
DR PANTHER; PTHR10166; VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED; 1.
DR Pfam; PF08473; VGCC_alpha2; 1.
DR Pfam; PF13519; VWA_2; 1.
DR Pfam; PF08399; VWA_N; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022673};
KW Calcium channel {ECO:0000256|ARBA:ARBA00022673};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022673};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007755};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022882};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT DOMAIN 286..491
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 203..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..224
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1252 AA; 143347 MW; DF32F81E359919FF CRC64;
MIFSSLEARD GVLGESEEEW RNTHRIARRA SKYKSMNARV EDKSGEELVN IISENVSRML
RRKMDAITCI RIAAEEAAEN WDPSLLDGNF SYVSGKCSPV IGHDSANKKK HCDIHKKNVT
VFRDMELISD SHFYDIPVNT TYSSVHIPTN VYDLTQDVTK DIARTEPLDD VFRQNYESDP
ALSWQYFGTV TGILRQYPAM QWRTNPEDTN DDDDDDDDDN DDNMIDNNNN NNNNNNNNVS
KNNNKNIDDV NDDDDGNNDD NDKSSADQYD CRVRSWFIEA ATCSKDMVIL MDVSGSMTGF
GKTIAKTTVN SILDTLSNND FVTLLKYSNE TTELVPCFKD MLIQATPENL DTFKKSMDKI
DTDNVANLTE AFTKAFSLLK TYREERGCDA DSPCNQLIML VTDGVPGGKL GNNLKEVFKK
WNWNENSTHI PVRVFTYLIG KEAIKMDELQ WMVRSCLNRG DCKHIQTQEE VSEQVLKYIP
VVARPLVLQS VVHPIVWTHA YADITNPALA AWLWWVMKHG QQKSRLEKYL KGKRLGVRIN
EDAIYIQQLH KDENIEEDSS TLNTTTWQEY SLLTSVSTPV FDRKSYNSNI TDATNDTLFG
VAGTDVPIDD IRKLTLPYKL GVNGYAFIVS NNGYVILHPD LRPVYKGRLK KNYNSIDLTE
VEILDDGREP RNPGPELLEL RSALVDHKRG NMMGIPVKLH YDNNRRVNLE KRDYFYAPLP
GTPFGLAVVL PNYGTTWIKV GDEIRRNQNK NVNVSDYFVG DHWRVHPSWV YCRYHYLEGH
EFNKPEDELR HFLALMSRPG WRWSEQYEAY SSIDEDLDEE PNCGRQTLKH DDYYCNKELM
QLLVFDAKAT NNSFRGDYME NLSSRARDLA HNYGIFIRFI ATQSGLTRWH HLKVSKLPNV
DDSIVFGDLH RRAVNEPWYK GAIFQSELDS ESISLSVPWE AGADAIVTAS MSLSPKDGGK
KAPAAVVGFQ MPMKDLYKQF IALTSDNQTT NTIINCAHNW IDCYLLDQNG YVVISDAHND
TGQFMGTQEG AVMLSMVKQG LYNPVDIYDY QAWCQEKRID NSANSLMEPL QHIARLLLWF
LLRLIWYATQ FVNLPGIYGK VHFDEDAPDP PPPPKSYLYH YPCDQKRTLY MLNETVAAKG
VTNHSDYCSR PFYAQRVAHT NLLLVVVDSM YPTCYKRLEV TPVNISPLEY TNSTGDKPCH
KIPLNTLKRR RLKNCFTEHP LEHVTYGCGT SELMVSLSLL YITVARILYI FI
//
