ID F4WM37_ACREC Unreviewed; 826 AA.
AC F4WM37;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Histone acetyltransferase GCN5 {ECO:0000256|ARBA:ARBA00019713};
GN ORFNames=G5I_06870 {ECO:0000313|EMBL:EGI64681.1};
OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS echinatior).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Acromyrmex.
OX NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN [1] {ECO:0000313|EMBL:EGI64681.1}
RP NUCLEOTIDE SEQUENCE.
RA Nygaard S., Zhang G.;
RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT adaptations to social evolution and fungus farming.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. GCN5 subfamily.
CC {ECO:0000256|ARBA:ARBA00008607}.
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DR EMBL; GL888217; EGI64681.1; -; Genomic_DNA.
DR AlphaFoldDB; F4WM37; -.
DR STRING; 103372.F4WM37; -.
DR eggNOG; KOG1472; Eukaryota.
DR InParanoid; F4WM37; -.
DR Proteomes; UP000007755; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR037800; GCN5.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR009464; PCAF_N.
DR PANTHER; PTHR45750; GH11602P; 1.
DR PANTHER; PTHR45750:SF3; HISTONE ACETYLTRANSFERASE; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF06466; PCAF_N; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007755};
KW Transferase {ECO:0000313|EMBL:EGI64681.1}.
FT DOMAIN 525..671
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 773..826
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 74..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 826 AA; 94847 MW; 74F6F883422039FD CRC64;
MRGIALPESP AEALHVAGLA FRVRETRMPA KRSISEYPEL VSFRTIHLCS LLMASEDVNS
HTILNASEET AQSVTSISQE SNNKNVNSSK PQTQGNPMSN LQRIQQRKQQ TYNWPQEKKL
LKLANYSACQ TQDCKCTGWK NAQSIIKSPK GEIQQPLISF SDSCKMCIHP LENHIKHLSV
QSDDEINRLL RMAIDADNIL TCSHREIDPD TKKVYFYLYK LLRNCILSMT KPIVEGPLGQ
PPFERPNIAK AVMNFVLYKF SHLPPADWQI MCDTAKMFLH CLNFWNFEAP SARQATINAD
EAPAYKINYT RWLVFCHVPA FCDSLPHHDT PLVFGKTLLQ AVFKRLCRDL MNKCHNERDK
ITPEKRIIVL THLPKFLSAL EAEIYSDSSP MWDPEFKQAP PSHAQAALES KAQQRKTGEF
EKVIITPNEK DNYTTINISP GIRRLSEKRF YFEGRSDAKK RKNEEVFEDL PDETVAEIVA
TINDPNYMYG PDAVFPPDVP RDETAKIEES RKIIEFHVVG NSLTQPVSKQ TMLWLIGLHN
VFSHQLVRMP KEYISQFVFD PKHKTLALIK SGRPIGGICF RMFPTQGFTE IVFCAVTSQE
QVKGYGTHLM NMLKDYHIKN NILHFLTFAD EFAIGYFKKQ GFSKDIKLPK PMYHGYIKDY
EGATLMHCEL NAKIVYTEFT AVLRKQKEIV KKLIYQRQQD IQKIHPGLTC FKDGVKSIPV
ESIPGIRETG WKNYAQTRTR GVVKGTQGSE LIDCMDMSES LYNTLNSVLN SVKNHISAWP
FLEPVDKDEV PDYYDHIKYP MDLKTMDERL KSKYCVTRRL FIADMT
//
