ID F4X9S8_9FIRM Unreviewed; 650 AA.
AC F4X9S8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=V-type ATP synthase subunit I {ECO:0000256|RuleBase:RU361189};
GN ORFNames=HMPREF0866_00039 {ECO:0000313|EMBL:EGJ47106.2};
OS Ruminococcaceae bacterium D16.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX NCBI_TaxID=552398 {ECO:0000313|EMBL:EGJ47106.2, ECO:0000313|Proteomes:UP000002801};
RN [1] {ECO:0000313|Proteomes:UP000002801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D16 {ECO:0000313|Proteomes:UP000002801};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA Sibley C.D., White A.P., Crowley S., Surette M.G., Strauss J.C.,
RA Ambrose C.E., Allen-Vercoe E., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium sp. D5.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EGJ47106.2, ECO:0000313|Proteomes:UP000002801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D16 {ECO:0000313|EMBL:EGJ47106.2,
RC ECO:0000313|Proteomes:UP000002801};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Sibley C.D., White A.P.,
RA Crowley S., Surette M.G., Strauss J.C., Ambrose C.E., Allen-Vercoe E.,
RA Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Ruminococcaceae bacterium D16.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGJ47106.2}.
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DR EMBL; ADDX02000001; EGJ47106.2; -; Genomic_DNA.
DR AlphaFoldDB; F4X9S8; -.
DR STRING; 552398.HMPREF0866_00039; -.
DR eggNOG; COG1269; Bacteria.
DR HOGENOM; CLU_025558_1_0_9; -.
DR OrthoDB; 9803814at2; -.
DR Proteomes; UP000002801; Unassembled WGS sequence.
DR GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR Gene3D; 1.20.1460.20; -; 1.
DR Gene3D; 3.30.70.2170; -; 1.
DR Gene3D; 3.30.70.2750; -; 1.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Reference proteome {ECO:0000313|Proteomes:UP000002801};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 371..395
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 407..429
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 461..481
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 502..530
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 542..561
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT COILED 109..136
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 236..263
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 650 AA; 72483 MW; 7142C0177C75FD3A CRC64;
MAIVKMKGLR LLAMRSDREA LLELLQGMGC VEIDEPDQDP QTWQGLLSQL GNQTLSRPDG
QALSQAREDL QAAQRALAVL KRHGDKGRGL LAPRPRLTRQ QLFDGEEQGK QAVQQVLEAD
RQLAALEAQH SKLLTQRAAL APWLELNIPL DTASTQEMVV QFGTVTAGVE LEQVQRAVEG
ASELAQLTQA SVDRDVRYCL LVCHTSAQEE VLQALRDFGW SRMNLSGWTG TAKENDQRIA
RELEQNEQET AQAEQQLAQL TSLAEPIRQA ADRASVRINR EEGRSRLLDT EKTFLLEGWV
PAEKWPELES QLKNYPCAWE LRDPTEEEYP KVPVKLKNNW FTRPLSMVTE MYSLPAYNGL
DPNPLMAPFF ILFYGIMMAD MGYGLLMMIA SVVVLKKSRP RAGMHNFFAL LGLCGVSTFI
MGAVTGGFFG DFIPQLLKLI NPESTFVWFW PTLFTPLEDT MMILVGAMAL GFVQILVGMA
ISFVKKLRRG QVMDAIWEEV TWWVVFAGLA LAILGVTNLV IILGGVMVVA GPILTEKGFG
KITGIFGSLY NHVTGYFGDI LSYSRLMALM LAGSVIAQVF NTLGAIPGNV VIFIIISMLG
NALNFALNLL GCYVHDLRLQ CLEYFNKFYE DGGKPFRPMK LDTNYYDVVK
//
