ID F4XRP3_9CYAN Unreviewed; 1258 AA.
AC F4XRP3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Polyketide synthase module {ECO:0000313|EMBL:AEF01447.1, ECO:0000313|EMBL:EGJ32721.1};
GN ORFNames=LYNGBM3L_03470 {ECO:0000313|EMBL:EGJ32721.1};
OS Moorena producens 3L.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Moorena.
OX NCBI_TaxID=489825 {ECO:0000313|EMBL:EGJ32721.1, ECO:0000313|Proteomes:UP000003959};
RN [1] {ECO:0000313|EMBL:AEF01447.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=3L {ECO:0000313|EMBL:AEF01447.1};
RA Jones A.C., Monroe E.A., Podell S., Hess W.R., Klages S., Esquenazi E.,
RA Niessen S., Hoover H., Rothman M., Lasken R., Yates J.R.III., Reinhardt R.,
RA Kube M., Burkhart M., Allen E., Gerwick W.H., Gerwick L.;
RT "Genomic insights into the physiology and ecology of the marine filamentous
RT cyanobacterium Moorea producens.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000003959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3L {ECO:0000313|Proteomes:UP000003959};
RX PubMed=21555588; DOI=10.1073/pnas.1101137108;
RA Jones A.C., Monroe E.A., Podell S., Hess W.R., Klages S., Esquenazi E.,
RA Niessen S., Hoover H., Rothmann M., Lasken R.S., Yates J.R.III.,
RA Reinhardt R., Kube M., Burkart M.D., Allen E.E., Dorrestein P.C.,
RA Gerwick W.H., Gerwick L.;
RT "Genomic insights into the physiology and ecology of the marine filamentous
RT cyanobacterium Lyngbya majuscula.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:8815-8820(2011).
RN [3] {ECO:0000313|EMBL:EGJ32721.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=3L {ECO:0000313|EMBL:EGJ32721.1};
RA Jones A.C., Monroe E.A., Podell S., Hess W.R., Klages S., Esquenazi E.,
RA Niessen S., Hoover H., Rothmann M., Lasken R.S., Yates J.R.III.,
RA Reinhardt R., Kube M., Burkart M.D., Allen E.E., Dorrestein P.C.,
RA Gerwick W.H., Gerwick L.;
RT "Genomic insights into the physiology and ecology of the marine filamentous
RT cyanobacterium Lyngbya majuscula.";
RL Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2011).
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DR EMBL; HQ696502; AEF01447.1; -; Genomic_DNA.
DR EMBL; GL890906; EGJ32721.1; -; Genomic_DNA.
DR RefSeq; WP_008184028.1; NZ_MKZR01000001.1.
DR eggNOG; COG3321; Bacteria.
DR HOGENOM; CLU_000022_35_7_3; -.
DR OrthoDB; 499075at2; -.
DR Proteomes; UP000003959; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF14765; PS-DH; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
FT DOMAIN 3..427
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 1258 AA; 138957 MW; BFD7829CF1BF8819 CRC64;
MNKEPIAIIG MGCRFPGAKN PEEFWELLCN GIDAITEVPA SRWDNELFYD ADISKPGKTN
SRWGGFLEQV DRFDPNFFGI SPRETQTMDP QQRLLLELAW EALEDAGQPP EELAGTPTGV
FMGVSSFDYY ELIAQNPSNF STYTGTGNLN CINANRLSYF FDFHGPSMAI DTACSSSLVA
VHLACQSLWS GESSLALVGG VHMVTSPWMS VAYAQGGFMA ADGRCKTFDA KADGYVRSEG
AGLVILKPLS LALANRDRIY ALVKGSAVNQ DGYSNGLTAP NPLAQEAVLR AAYKNAGVSP
GQVQYIEAHG TGTKLGDPME MKALGAVLSV GRAPGDYCAV GSAKTNIGHL EAPAGIAGLI
KVALSLHYRQ IPPSLNFTEP NPYIKFDEIP LRVQETLTPW PEKSMPAYAG VSSFGFGGTN
SHVVLAEVEN KELLIGNTEE KRLERPVNLL TLSAKTEEAL EQLVTGYEHH LKKHSELAIG
DVCYTANVGR THFKYRLAVV TKSTEQLQEQ LKATAEREET PGVFKGQKIG RKRPKVAFLF
TGQGSQYVNM GRQLYESQPT FRQGLDQCDE ILRPYLEHSL LEVLYPQEAQ NSSSSLLDQT
AYTQPALFAI EYALAKLWFS WGIKPNVVMG HSVGEYVAAC IAGVFSLEDG LKLIAMRGRL
MQQLPAGGKM VSLLASEERV KKAIADYSSQ EGLEKSAVSI AAINGPESIV ISGESEAIAS
ICSKLEVMGV KTKQLQVSHA FHSPLMEPML AKFETIAKQV TYNKPRIKLI SNVTGKLVGD
EITSAEYWVN HVQQPVSFAQ SLKNTYQEGC KLFLEIGPKP ILLGMGRQCV PEDVGVWLPS
LRPGVDEWQQ MLSSLGQLYV KGAKIDWSGF DSDYSRQKVA LPTYPFQRER YWIETNNNFW
PKQQFSKGEN LHPLLGQKLN CAGEQQIFAS QIGEKSPNYL SHHRVFNQAL FPTTGYLEIA
IAAGNHQLKT PQIVIEDLTI GRGWILPAGE LTNAQTILTP TDNQSYKFQI FSQPEQQEWR
LHTTGKIRKE STPPTQTKID LEKYKSEFNQ AIEVKQHYQK CQQVGIDYGN SFQGIQELWS
GTNQALAYIK LPEELITQTR DYNFHPALLD AALQVIFQAL PATDSDQTYL PVGIEEFKLY
KNPGLSLWAY ASVTSPEVKT PESLTTLVTI VTPSGEIIAN LKGLQLKLAT KQTLLGTETE
SIENWLYEVE WRSQGILGKL LPPDFLRPPV EIAQKLAPTL TELVTQVDQK RTGSMKQA
//
