ID F4YTA6_MORMO Unreviewed; 365 AA.
AC F4YTA6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:ADL62722.1};
OS Morganella morganii subsp. sibonii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Morganella.
OX NCBI_TaxID=180435 {ECO:0000313|EMBL:ADL62722.1};
RN [1] {ECO:0000313|EMBL:ADL62722.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=8293-1 {ECO:0000313|EMBL:ADL62722.1};
RA Parikh R.Y., Thakkar K.N., Mhatre S.S., Patole M.S., Shouche Y.S.;
RT "Molecular phylogenetic analysis of Morganella sp. RP-42.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; HM122061; ADL62722.1; -; Genomic_DNA.
DR AlphaFoldDB; F4YTA6; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 308..365
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADL62722.1"
FT NON_TER 365
FT /evidence="ECO:0000313|EMBL:ADL62722.1"
SQ SEQUENCE 365 AA; 40627 MW; 98ECBB7132D22174 CRC64;
VSGGLHGVGV SVVNPLSEKL ELVIRRDGKV HEQIYRHGEP QDRLTIVGET DKTGTRVRFW
PSMNTFKGET EFQYDILAKR LRELSFLNSG VSIRLVDKRD GKEDHFHYEG GIKAFVEYLS
RAKTSIHNNV FYFSTEKDDI GVEVSMQWND SFQENVYCFT NNIPQRDGGA HLAGFRAAMT
RTLNSYIEKE GLNKKSKVST TGDDAREGLV AVISVKVPDP KFSSQTKDKL VSSEVKTAVE
TLMNEKLSEY LDENPNDTKI IVGKIIDAAR AREAARRARE MTRRKGALDL AGLPGKLADC
QERDPAFSEL YLVEGDSAGG SAKQGRNRKN QAILPLKGKI LNVEKARFDK MLGSQEVATL
ITALG
//
