ID F5AQY5_AERSA Unreviewed; 308 AA.
AC F5AQY5;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:AEE38745.1};
OS Aeromonas salmonicida.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=645 {ECO:0000313|EMBL:AEE38745.1};
RN [1] {ECO:0000313|EMBL:AEE38745.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MDC 148 {ECO:0000313|EMBL:AEE38745.1};
RX PubMed=21353754; DOI=10.1016/j.syapm.2010.11.014;
RA Martinez-Murcia A.J., Monera A., Saavedra M.J., Oncina R.,
RA Lopez-Alvarez M., Lara E., Figueras M.J.;
RT "Multilocus phylogenetic analysis of the genus Aeromonas.";
RL Syst. Appl. Microbiol. 34:189-199(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; HQ442681; AEE38745.1; -; Genomic_DNA.
DR AlphaFoldDB; F5AQY5; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 270..308
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEE38745.1"
FT NON_TER 308
FT /evidence="ECO:0000313|EMBL:AEE38745.1"
SQ SEQUENCE 308 AA; 34030 MW; 991978F3CEF5A91B CRC64;
EPQAPLKQIG DSSSGTGTEV RFWPSPTIFT DTLYHYEILA KRLRELSFLN SGVSIRLQDE
RDGREVHFCY EGGIKAFVEY LNQNKTPIHP KVFHFSTEQD GIGVEVAMQW NDAYQEGVYC
FTNNIPQRDG GTHLVGFRTA LTRTLNTYMD KEDYSKKAKS AASGDDVREG LIAVISVKVP
DPKFSSQTKD KLVSSEVKTA VEQAMGEKLG EFLLENPGDA KIVVNKIIDA ARPREAARKA
RELTRRKGAL DIAGLPGKLA DCQEKDPALS ELYIVEGDSA GGSAKQGRNR KNQAILPLKG
KILNVEKA
//
