ID F5GZY6_HUMAN Unreviewed; 124 AA.
AC F5GZY6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=LTO1 maturation factor of ABCE1 {ECO:0000313|Ensembl:ENSP00000444112.1};
GN Name=LTO1 {ECO:0000313|Ensembl:ENSP00000444112.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000444112.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000444112.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [2] {ECO:0007829|PubMed:21406692}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21406692; DOI=10.1126/scisignal.2001570;
RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T.,
RA Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.;
RT "System-wide temporal characterization of the proteome and phosphoproteome
RT of human embryonic stem cell differentiation.";
RL Sci. Signal. 4:RS3-RS3(2011).
RN [3] {ECO:0007829|PubMed:22814378}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN [4] {ECO:0000313|Ensembl:ENSP00000444112.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LTO1 family.
CC {ECO:0000256|ARBA:ARBA00038090}.
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DR EMBL; AP001888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F5GZY6; -.
DR SMR; F5GZY6; -.
DR MassIVE; F5GZY6; -.
DR MaxQB; F5GZY6; -.
DR PeptideAtlas; F5GZY6; -.
DR ProteomicsDB; 25168; -.
DR Antibodypedia; 58325; 93 antibodies from 20 providers.
DR Ensembl; ENST00000539414.5; ENSP00000444112.1; ENSG00000149716.13.
DR UCSC; uc058eqw.1; human.
DR HGNC; HGNC:17589; LTO1.
DR VEuPathDB; HostDB:ENSG00000149716; -.
DR GeneTree; ENSGT00390000009426; -.
DR Proteomes; UP000005640; Chromosome 11.
DR Bgee; ENSG00000149716; Expressed in right hemisphere of cerebellum and 111 other cell types or tissues.
DR ExpressionAtlas; F5GZY6; baseline and differential.
DR InterPro; IPR019191; Essential_protein_Yae1_N.
DR PANTHER; PTHR28532; GEO13458P1; 1.
DR PANTHER; PTHR28532:SF1; LTO1 MATURATION FACTOR OF ABCE1; 1.
DR Pfam; PF09811; Yae1_N; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:F5GZY6,
KW ECO:0007829|MaxQB:F5GZY6};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 22..60
FT /note="Essential protein Yae1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09811"
SQ SEQUENCE 124 AA; 13932 MW; E427B9D8DBC02DDF CRC64;
MAGSQDIFDA IVMADERFHG EGYREGYEEG SSLGVMEGRQ HGTLHGAKIG SEIGCYQGFA
FAWKCLLHSC TTEKDSRKMK VLESLIGMIQ KFPYDDPTYD KLHEDLDKIR GKFKQVRALC
VSSC
//
