ID   F5NU54_SHIFL            Unreviewed;       302 AA.
AC   F5NU54;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Sulfatase family protein {ECO:0000313|EMBL:EGK38289.1};
DE            EC=3.1.6.- {ECO:0000313|EMBL:EGK38289.1};
GN   ORFNames=SFK227_1652 {ECO:0000313|EMBL:EGK38289.1};
OS   Shigella flexneri K-227.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=766147 {ECO:0000313|EMBL:EGK38289.1, ECO:0000313|Proteomes:UP000004520};
RN   [1] {ECO:0000313|EMBL:EGK38289.1, ECO:0000313|Proteomes:UP000004520}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K-227 {ECO:0000313|EMBL:EGK38289.1,
RC   ECO:0000313|Proteomes:UP000004520};
RA   Rasko D., Redman J., Daugherty S.C., Tallon L., Sadzewicz L., Jones K.,
RA   Santana-Cruz I., Liu X.;
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- PTM: The conversion to 3-oxoalanine (also known as C-formylglycine,
CC       FGly), of a serine or cysteine residue in prokaryotes and of a cysteine
CC       residue in eukaryotes, is critical for catalytic activity.
CC       {ECO:0000256|PIRSR:PIRSR600917-52}.
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGK38289.1}.
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DR   EMBL; AFGY01000020; EGK38289.1; -; Genomic_DNA.
DR   AlphaFoldDB; F5NU54; -.
DR   PATRIC; fig|766147.3.peg.1620; -.
DR   Proteomes; UP000004520; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR42693:SF49; SULFATASE-RELATED; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EGK38289.1}.
FT   DOMAIN          42..288
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   MOD_RES         68
FT                   /note="3-oxoalanine (Ser)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600917-52"
SQ   SEQUENCE   302 AA;  33724 MW;  6AE3AB29640F8228 CRC64;
     MDDLGYGQLP FDKGSFDPKT MENREVVDTY KIGIDKAIEA AQKSTPTLLS LMDEGVRFTN
     GYVAHGVSGP SRAAIMTGRA PARFGVYSNT DAQDGIPLTE TFLPELFQNH GYYTAAVGKW
     HLSKISNVPV PEDKQTRDYH DNFTTFSAEE WQPQNRGFDY FMGFHAAGTA YYNSPSLFKN
     RERVPAKGYI SDQLTDEAIG VVDRAKTLDQ PFMLYLAYNA PHLPNDNPAP DQYQKQFNTG
     SQTADNYYAS VYSVDQGVKR ILEQLKKNGQ YDNTIILFTS DNGAVIDGPL PLEVVNKNWP
     PS
//