ID F5T854_9FIRM Unreviewed; 351 AA.
AC F5T854;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Addiction module antidote protein HigA {ECO:0000313|EMBL:EGL37754.1};
GN Name=higA {ECO:0000313|EMBL:EGL37754.1};
GN ORFNames=HMPREF9124_0033 {ECO:0000313|EMBL:EGL37754.1};
OS Oribacterium sp. oral taxon 108 str. F0425.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Oribacterium.
OX NCBI_TaxID=904296 {ECO:0000313|EMBL:EGL37754.1, ECO:0000313|Proteomes:UP000003787};
RN [1] {ECO:0000313|EMBL:EGL37754.1, ECO:0000313|Proteomes:UP000003787}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0425 {ECO:0000313|EMBL:EGL37754.1,
RC ECO:0000313|Proteomes:UP000003787};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGL37754.1}.
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DR EMBL; AFIH01000001; EGL37754.1; -; Genomic_DNA.
DR RefSeq; WP_009429381.1; NZ_AFIH01000001.1.
DR AlphaFoldDB; F5T854; -.
DR STRING; 904296.HMPREF9124_0033; -.
DR eggNOG; COG3093; Bacteria.
DR OrthoDB; 9796786at2; -.
DR Proteomes; UP000003787; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR013430; Toxin_antidote_HigA.
DR NCBIfam; TIGR02607; antidote_HigA; 1.
DR PANTHER; PTHR43236; ANTITOXIN HIGA1; 1.
DR PANTHER; PTHR43236:SF1; BLL7220 PROTEIN; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
FT DOMAIN 16..70
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 351 AA; 39624 MW; 9072C00E11B19E1A CRC64;
MVRSRSIIAT PPGATIKEQL KDRGMSQKEF AARMDMSEKH ISKLINGEVQ LTPEVAIRLE
FVLGVPAKFW NNLEAIYREK IIKAEAENTM DKDEEIAKKL PYNEMAKFGW VPETRVLREK
VVNLRKYFEI VELSLLNNIQ ITRIACRRRL AITEKSDLAL LAWTQEAKIK ARDVKTAPIN
IKGLMNIIPK IRLMTVMKAK EFCPKLKSML AECGIALVFL PHLQGSFLQG TSFIDGNKIV
VGLTARGKDA DKFWFSLFHE LAHIILGHIG QTNGTSEDDE QAANFWSGDT LIPGNDFSEF
IDRKCFSVSS IRAFAEKQGI APGIVVVRLQ NEGCIKHSAL NELKEHYKIV V
//
