ID F5YYT6_MYCSD Unreviewed; 1204 AA.
AC F5YYT6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=5-oxoprolinase {ECO:0000313|EMBL:AEF34251.1};
GN Name=oplA {ECO:0000313|EMBL:AEF34251.1};
GN OrderedLocusNames=JDM601_0251 {ECO:0000313|EMBL:AEF34251.1};
OS Mycolicibacter sinensis (strain JDM601) (Mycobacterium sinense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacter.
OX NCBI_TaxID=875328 {ECO:0000313|EMBL:AEF34251.1, ECO:0000313|Proteomes:UP000009224};
RN [1] {ECO:0000313|EMBL:AEF34251.1, ECO:0000313|Proteomes:UP000009224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JDM601 {ECO:0000313|EMBL:AEF34251.1,
RC ECO:0000313|Proteomes:UP000009224};
RX PubMed=21685274; DOI=10.1128/JB.05291-11;
RA Zhang Z.Y., Sun Z.Q., Wang Z.L., Wen Z.L., Sun Q.W., Zhu Z.Q., Song Y.Z.,
RA Zhao J.W., Wang H.H., Zhang S.L., Guo X.K.;
RT "Complete genome sequence of a novel clinical isolate, the nontuberculous
RT Mycobacterium strain JDM601.";
RL J. Bacteriol. 193:4300-4301(2011).
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002329; AEF34251.1; -; Genomic_DNA.
DR AlphaFoldDB; F5YYT6; -.
DR STRING; 875328.JDM601_0251; -.
DR KEGG; mjd:JDM601_0251; -.
DR eggNOG; COG0145; Bacteria.
DR eggNOG; COG0146; Bacteria.
DR HOGENOM; CLU_002157_0_1_11; -.
DR Proteomes; UP000009224; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009224}.
FT DOMAIN 7..184
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 205..497
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 509..670
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 693..1203
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 1204 AA; 127672 MW; 21C814B0FDD2F34F CRC64;
MSTMWQFWID RGGTFTDIVA RRPDGRLLTH KLLSENPDRY RDAAVAGIRA LLQVPDDAPI
PPGTVEAVRM GTTVATNALL ERAGERTLLV ITRGFGDALR IGYQNRPRIF DRHIVLPDQL
YERTVEVDER VGADGSVLRA PDLDALGEAL RAAHADGIRS VAVVCLHSYR NPAHEQAIGA
LAEQLGFSQI SLSSEVSPLP KLIPRGDTAV IDAYLSPVLR RYVAQVADEL RGVRLMFMQS
NGGLTAADHF RGKDAILSGP AGGIVGMVAM SALAGFDAVI GFDMGGTSTD VSHYSAASGG
YERVFTTEVA GVRLRAPMLH IHTVAAGGGS ILHFDGSRYR VGPESAGADP GPACYRRGGP
LTVTDANVLL GRIQPAHFPP VFGPSGDEPL DAAAVRRGFS DLAAAIHAAT GQNSAARSPE
QVAEGFLRIA VANMANAVKK ISVAKGHDIT RYALTTFGGA GGQHACAVAD ELGIRTVLVP
PMAGVLSALG IGLADTTVIR ERSVEARLDS AAPELGDVAD GLERQARAAL ADQDIPADRI
RVTRRVHLRY QGTDTAIPVE LADIAQMTAA FEDIHRSMYS FLMERPLIAE TVAVEATGLT
EQPELADQTA SGTGRHPAEA VRLYTGGSWR DAPLYRRDAI TPADVVSGPA IIAEDNATTV
VDDGWRAQLT ADGQLLLRRT AAAAPDNAGT HADPVLLEIF NNLFMAIAEQ MGTRLEATAQ
SVNIRERLDF SCALFDADGN LVANAPHIPV HLGSMGATVK EVIARRAGQL RPGQVYAVND
PYHGGTHLPD ITVITPVYRD SASPDDPVLF FVASRGHHAE IGGTTPGSMP ADSSTVDEEG
VLFDNWLLVD DGRFREAQTR SLLTGGRFPS RSPDTNLADL RAQVAANQKG IDEIRTMIDH
FGLDVVQAYM RHVQDNAEEA VRRVIDSLDD GEYRYVMDSG ATIAVRVTVD RAARSATIDF
DGTSPQLATN FNAPSSVASA AVLYVFRTLV EDDIPINDGC LRPLRITIPD ATMLAPGYPA
AVVAGNVETS QAITGALLAA LRVQAEGSGT MNNVTFGNAG HQYYETLGSG SGAGDGFDGA
AVVQTHMTNS RLTDPEVLEM RFPVLLREFA IRRGSGGSGR WTGGDGGLRR IEFREPMTVS
VLSGHRAVAP YGMAGGSPGA LGHNRVMRAD GEVTELAGCD STDMASGDVL VIETPGGGGY
GQPR
//
